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polyprenol/amnesia
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Ropren(®) is a polyprenol preparation from coniferous plants that ameliorates cognitive deficiency in a rat model of beta-amyloid peptide-(25-35)-induced amnesia.
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This study assesses the efficacy of a fixed dose of Ropren(®) (a plant preparation isolated from the neutral fraction of an extract of spruce needles) on cognitive impairment in rats with β-amyloid peptide-(25-35)-induced amnesia. Ropren(®) was administered at a dose of 8.6mg/kg for 28 days, per os,
[Effect of new polyprenol drug ropren on anxiety-depressive-like behavior in rats with experimental Alzheimer disease].
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Influence of the chronic administration of ropren (Trademark)--a plant preparation based on the neutral fraction of extract of spruce and pine needles--on affective status in male rats with amyloid peptide (Abeta(25-35)) induced amnesia has been studied. Ropren was administered per os in a dose of
Cognitive-enhancing activities of the polyprenol preparation Ropren® in gonadectomized β-amyloid (25-35) rat model of Alzheimer's disease.
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The present preclinical study was designed to examine the effects of prolonged Ropren® administration (8.6 mg/kg, orally, once daily, 28 days) in a β-amyloid (25-35) rat model of Alzheimer's disease following gonadectomy. The experimental model was created by intracerebroventricular injection of
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