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s methyl l cysteine/kanker
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Ligand substitution reactions and cytotoxic properties of [Au(L)Cl2](+) and [AuCl2(DMSO)2]+ complexes (L=ethylenediamine and S-methyl-l-cysteine).
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We have studied the kinetics of the complex formation of gold(III) complexes, [AuCl(2)(en)](+) (dichlorido(ethylenediamine)aurate(III)-ion) and [AuCl(2)(SMC)] (dichlorido (S-methyl-l-cysteine)aurate(III)) with four biologically N-donor nucleophiles. It was shown that studied ligands have a high
The cytotoxic effects of some selected gold(III) complexes on 4T1 cells and their role in the prevention of breast tumor growth in BALB/c mice.
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OBJECTIVE
to investigate the cytotoxic activity of newly synthesized gold(III) complexes [AuCl(2)(en)](+), [AuCl(2) (SMC)](+), [AuCl(2)(DMSO)(2)(+) (en: ethylenediamine, SMC: S-methyl- L-cysteine and DMSO: for dimethylsulfoxide) in 4T1 mouse breast cancer cell line in vitro and in vivo and to
Effect of s-methyl-L-cysteine on oxidative stress, inflammation and insulin resistance in male wistar rats fed with high fructose diet.
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BACKGROUND
S-methyl cysteine (SMC) is a hydrophilic cysteine-containing compound naturally found in garlic and onion. The purpose of the present study was to investigate the protective effect of SMC on oxidative stress, inflammation and insulin resistance in an experiment of metabolic
Identification of human urinary biomarkers of cruciferous vegetable consumption by metabonomic profiling.
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Consumption of cruciferous vegetables (CVs) is inversely correlated to many human diseases including cancer (breast, lung, and bladder), diabetes, and cardiovascular and neurological disease. Presently, there are no readily measurable biomarkers of CV consumption and intake of CVs has relied on
Influence of the chloride concentration on ligand substitution reactions of [Pt(SMC)Cl(2)] with biologically relevant nucleophiles.
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The kinetics and mechanism of ligand substitution reactions of [Pt(SMC)Cl(2)] (SMC = S-methyl-l-cysteine) with biologically relevant ligands were studied as a function of chloride and nucleophile concentrations at pH 2.5 and 7.2. It was observed that the slope and intercept obtained from the linear
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