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Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa.
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Anxiety and depression are pathologies that affect human beings in many aspects of life, including social life, productivity and health. Cannabidiol (CBD) is a constituent non-psychotomimetic of Cannabis sativa with great psychiatric potential, including uses as an antidepressant-like and
Cannabinoid receptor CB1-like and glutamic acid decarboxylase-like immunoreactivities in the brain of Xenopus laevis.
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Investigation of the cannabinoid system in a vertebrate group phylogenetically distant from mammals might improve understanding of its physiological role. Thus, in the present study, the distribution of the cannabinoid CB1 receptor has been investigated in the brain of Xenopus laevis (anuran
Cannabinoids: just like any other medication?
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Cannabinoids in functional tic-like movements.
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Do cannabinoids exhibit a tyramine-like effect?
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The major constituent of the cannabis plant, Δ(9)-tetrahydrocannabinol, has stimulatory and depressant effects on cardiovascular functions. There is evidence from an in vivo study on the urethane-anaesthetized rat that part of the stimulatory effects is related to a tyramine-like activity. In the
Polydrug use, cannabis, and psychosis-like symptoms.
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OBJECTIVE
To examine psychosis-like symptoms in users of legal and illicit drugs.
METHODS
Schizotypal Personality Questionnaire (SPQ) scores were compared in groups of people with different exposure to cannabis, with the use of other drugs serving as a covariate. Supplemental analyses compared users
Prolonged marijuana-like dysphoria after subcutaneous sumatriptan.
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License heritable gene editing like medical cannabis.
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European dimension of cannabinoid-like products use.
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The use of new psychoactive substances and the new patterns of drug use can have important public health and policy implications. Few countries have monitoring systems that are sensitive to this new phenomenon in the drug field, but methodological difficulties to detect them are considerable.
Cannabinoids enhance gastric X/A-like cells activity.
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It has been reported that cannabinoids may cause overeating in humans and in laboratory animals. Although, endogenous cannabinoids and their receptors (CB1) have been found in the hypothalamus, and recently also in gastrointestinal tract, the precise mechanism of appetite control by cannabinoids
Cannabinoid-like anti-inflammatory compounds from flax fiber.
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Flax is a valuable source of fibers, linseed and oil. The compounds of the latter two products have already been widely examined and have been proven to possess many health-beneficial properties. In the course of analysis of fibers extract from previously generated transgenic plants overproducing
Cannabis-induced erythema multiforme-like recurrent drug eruption.
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Purtscher-Like Retinopathy Associated with Synthetic Cannabinoid (Bonzai) Use
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Purtscher’s retinopathy is a microvascular occlusive disease initially described as retinal edema, cotton wool-like exudation, and hemorrhages occurring after severe head trauma. A similar clinical presentation called Purtscher-like retinopathy is associated with systemic diseases instead of trauma.
Acute cannabis intoxication mimicking brugada-like ST segment abnormalities.
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A 19 years old male presented with a syncopeal episode after heavy marihuana use. A 12 lead ECG demonstrated Brugada-like ST segment elevation in leads V1 and V2. Urine and blood toxicological studies upon admission demonstrated markedly elevated levels of Tetrahydrocannabinol (THC). A 2D
Three isoflavanones with cannabinoid-like moieties from Desmodium canum.
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Three further derivatives of 5,7,2',4'-tetrahydroxy-6-methyl isoflavanone have been isolated from the root extract of Desmodium canum and assigned the structures
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