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[Effect of Silybum marianum oil and legalon on lipid peroxidation and liver antioxidant systems in rats intoxicated with carbon tetrachloride].
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An oil obtained from the seeds of Saint-Mary thistle (Silybum marianum) and the drug legalon (silybinin) prepared from this plant produce an antioxidant effect on liver tissues of rats poisoned with carbon tetrachloride. Legalon (25 mg/kg) and the oil (2000 mg) reduced the level of lipid
Silymarin synthesis and degradation by peroxidases of cell suspension cultures of Silybum marianum.
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Treatment of Silybum marianum cell cultures with methyl jasmonate elicits the production of the antihepatotoxic drug silymarin and its release into the culture medium. In this work, we investigated the involvement of peroxidases (EC 1.11.1.7; donor hydrogen peroxidase oxido-reductase) in silymarin
Batch solvent extraction of flavanolignans from milk thistle (Silybum marianum L. Gaertner).
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Seeds of milk thistle (Silybum marianum L. Gaertner) contain silymarins and ca. 25% (w/w) of oil. A pre-treatment step involving refluxing with petroleum ether is usually performed before extraction of the silymarins using organic solvents. This paper compares the extraction of whole and defatted
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