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[Mechanism of action of antimutagens. II. Relationship between the antimutagenic effect of ionol and the stage of the mitotic cycle of Crepis capillaris L].
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When a synchronous population of Crepis capillaris L. cells was used as the experimental material, the repair of spontaneous and induced aberrations by antimutagens was established to take place at the G1 stage. A definite period within this stage when the repair proceeds is discovered.
[Mutagenic activity of antineoplastic agents under conditions of normal and artificial modification].
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Mutagenic effect of vincristine, vinblastine, thiophosphamide, sarcolysine and the supermutagen ethyleneimine was studied in Crepis capillaris germinating seeds at the G phase. Metabolic conditions, prolongation of cell cycle, specific activity of preparation as well as inhibition of DNA synthesis
[Mutagenic and antimutagenic activities of human whole blood, plasma and albumin].
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The seeds of Crepis capillaris were used to examine the mutagenic und antimutagenic properties of human whole blood, plasma, serum albumin and gamma-globulin by recording chromosomal and chromatid aberrations. The antimutagenic activity was determined by preliminary, simultaneous, and subsequent
[Quantitative and qualitative criteria for assessing the efficacy of antimutagens in an experiment].
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The antimutagenic effect of para-aminobenzoic acid, tocopherol, adenosine and caffeine has been studied in experiments with microorganisms, Crepis capillaris seed cells, human lymphocytes, murine bone marrow cells in vivo. The activity, of antimutagens, their nature and action range, effective
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