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succinic dehydrogenase/sembap

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Significant increase of liver succinic dehydrogenase (SDH, EC 1.3.99.1) activity was produced by carrageenin-induced edema in rats. Pretreatment with human placental extract inhibited the increased liver SDH activity in a dose-dependent manner. Placental extract was found to have little or no effect

Biomechanical characteristics of brain edema: the difference between vasogenic-type and cytotoxic-type edema.

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Some of the basic biomechanical properties of edematous brain tissue have yet to be clarified. Therefore we measured regional tissue compliance and swelling isotropy/anisotropy in cat brain during development of vasogenic-type and cytotoxic-type edema. In vasogenic-type edema induced by cryogenic

Hydrops of the organ of Corti.

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OBJECTIVE The authors would like to confirm a fluid pathway from the scala tympani to the organ of Corti, and to observe its morphological changes. METHODS A staining solution for succinic dehydrogenase was perfused with phenazine methosulfate in the scala tympani of living guinea pigs (n = 5) under

Metabolic changes in nicotinamide adenine dinucleotide in response to anthrax toxin.

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Bacillus anthracis produces a toxin both in vitro and in vivo which, when injected intravenously into rats, brings about the death of the animals accompanied by gross pulmonary edema. Lung tissue removed prior to death showed, in vitro, a 30% reduction in overall oxidative metabolism (Q(o2)),

[Experimental study on isolated testes with ischemia/reperfusion injury].

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OBJECTIVE To investigate the injury on isolated testes induced by ischemia/reperfusion(I/R), and the protective effect of Yisheng injection on the injury. METHODS Twenty-six isolated cadaver testes contributed by 13 persons were preserved with 4 degrees C 250 ml hypertonic citrate alloxuric (HCA)

A morphological and histochemical study of the scalded hairy mouse ear.

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The right ear of mice was scalded at 51 degrees C and 53 degrees C for 20 s, using the recently developed dip burn model, and examined morphologically and histochemically at intervals for 2 h postburn. The left, unburned ear served as control. Burned ears intended for light and electron microscopy

Anti-inflammatory effect of human placental extract: a biochemical mechanistic approach.

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Significant increase of liver succinic dehydrogenase (SHD) activity was produced by carrageenin-induced edema in rats. Pretreatment with human placental extract "Placentrex" inhibited the increased liver SHD activity in a dose-dependent manner. "Placentrex" was found to have no effect on the liver

Clinical, histologic, and histochemical study of imidocarb diproprionate toxicosis in goats.

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The toxic effects of imidocarb diproprionate (3,3'-bis [2 imidazolin-2yl]-carbanilde diproprionate) were evaluated in adult goats given (intramuscular injection) a lethal dose (6.75 mg/kg). The immediate clinical signs of toxicosis were transient excessive salivation and diarrhea. Anorexia, dyspnea,

Skeletal muscle fiber, nerve, and blood vessel breakdown in space-flown rats.

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Histochemical and ultrastructural analyses were performed postflight on hind limb skeletal muscles of rats orbited for 12.5 days aboard the unmanned Cosmos 1887 biosatellite and returned to Earth 2 days before sacrifice. The antigravity adductor longus (AL), soleus, and plantaris muscles atrophied

The histological and histochemical effects of ketotifen in allergic rhinitis.

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The effects of a three-month course of oral ketotifen on the histology and histochemistry of nasal mucosa, assessed on punch biopsy material, were studied in 30 adults with perennial allergic rhinitis. Ketotifen treatment was associated with reversal of the histopathology and enzyme changes in every

Comparative electron-microscopic investigation of postmortem human heart muscle biopsy.

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Based on Harvard criteria findings, comparative morphological investigation on postmortem heart muscle biopsy following coronary insufficiency after sudden cardiac death have been reported. The subendothelial layer of the left ventricular wall has revealed a severe interstitial edema, various types

Brain damage related to hemorrhagic transformation following cerebral ischemia and the role of K ATP channels.

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BACKGROUND Hemorrhagic transformation (HT) is a major factor limiting the use of thrombolytic treatment for stroke. Animal model can help us to understand HT. This study is to establish a HT model in rats to compare HT with uncomplicated cerebral infarction in neurobehavioral deficit, brain edema,
OBJECTIVE To investigate the molecular mechanisms of diaphragm injury in rats with liver cirrhosis. METHODS Thirty adult male Sprague-Dawley rats were randomized into control group (n=10) and carbon tetrachloride-induced liver cirrhosis group (LC group, n=20). In the 9th week, the rat body weight

Protective effects of oleanolic acid on cerebral ischemic damage in vivo and H(2)O(2)-induced injury in vitro.

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BACKGROUND Oleanolic acid (OA), a triterpenoid compound, exists in many plants. It has numerous bioactivities and has been used to treat hepatitis in China. However, few studies have reported its effect on the central nervous system, especially in ischemic stroke. OBJECTIVE To explore the protective
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