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testicular neoplasms/albumin
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The role of preoperative albumin to globulin ratio in predicting prognosis in testicular cancer patients
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Introduction and objectives: In recent years, the incidence of testicular cancer has increased, but mortality rates have decreased thanks to the improvements in treatment. Although primary tumor characteristics and serum tumor markers are
Single-nucleotide polymorphism in the 5-α-reductase gene (SRD5A2) is associated with increased prevalence of metabolic syndrome in chemotherapy-treated testicular cancer survivors.
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OBJECTIVE
Chemotherapy-treated testicular cancer survivors are at risk for development of the metabolic syndrome, especially in case of decreased androgen levels. Polymorphisms in the gene encoding steroid 5-α-reductase type II (SRD5A2) are involved in altered androgen metabolism. We investigated
Absence of relation between nutritional parameters and renal function in non-seminomatous testicular cancer patients.
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Earlier studies revealed that renal function is reduced in non-cancer patients with a malnutritional status. We have studied the effect of nutritional status on renal function in 46 patients with disseminated non-seminomatous testicular cancer treated with combination chemotherapy including
Possible risk of overestimation of renal function using cystatin C-based eGFR in testicular cancer survivors treated with cisplatin-based chemotherapy.
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BACKGROUND
Chronic kidney disease (CKD) is a major long-term morbidity of testicular cancer (TC) survivors cured by cisplatin-based chemotherapy. We conducted the present study to elucidate the usefulness of cystatin-based estimated glomerular filtration rates (eGFRcys) for diagnosis of CKD compared
Synthesis of alpha-fetoprotein and some other serum proteins in testicular tumors.
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Serum levels of alpha-fetoprotein were determined in 33 patients with testicular germ cell tumors and were normal in 11 patients with seminoma and in one patient with matured teratoma; high levels were observed in 19 of 21 patients with embryonal carcinoma, teratocarcinoma, or a mixed type of these
Hepatocellular carcinoma metastatic to the testis.
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A 57-year-old man had upper gastrointestinal signs and symptoms associated with testicular swelling and elevation of the serum alpha-fetoprotein level. Abdominal exploration revealed a large solitary liver mass and massively enlarged retroperitoneal lymph nodes, and a right scrotal exploration
Possible liver cell differentiation in testicular germ cell tumours.
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Germ cell tumours may imitate various structures of the developing embryo and foetus. Certain structures have, however, very rarely or never been observed in these tumours. Thus the presence of hepatic tissue in testicular germ cell tumours has not been reported. In a series of 37 non-seminomatous
Malondialdehyde and CA II autoantibody levels are elevated in children with undescended testes.
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OBJECTIVE
In the pathogenesis of sub-fertility/infertility and testicular cancer related to undescended testes, oxidative stress, inflammation and autoimmunity are important factors. Therefore, the present study was designed to determine serum oxidative stress markers and carbonic anhydrase (CA) II
New perspectives on the toxicity of etoposide.
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Etoposide has been used in the treatment of a wide variety of neoplasms, including small cell lung cancer. Kaposi's sarcoma, testicular cancer, acute leukemia, and lymphoma. Its current therapeutic use is limited by myelosuppression, particularly neutropenia. Pharmacodynamic studies of etoposide
Pharmacodynamics and long-term toxicity of etoposide.
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Etoposide has been used in the treatment of a wide variety of neoplasms, including small-cell lung cancer, Kaposi's sarcoma, testicular cancer, acute leukemia, and lymphoma. Its current therapeutic use is limited by myelosuppression, particularly neutropenia. Pharmacodynamic studies of etoposide
Treatment of Chylous Ascites with Peritoneovenous Shunt (Denver Shunt) following Retroperitoneal Lymph Node Dissection in Patients with Urologic Malignancies: Update of Efficacy and Predictors of Complications.
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Clinical value of fructose 1,6 bisphosphatase in monitoring renal proximal tubular injury.
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The usefulness of the gluconeogenic key enzyme fructose 1,6 bisphosphatase (FBPase), which is localized exclusively in the proximal nephron segment, as a marker compound to monitor injury of the proximal nephron segment during nephrotoxic therapy, was tested in a collective model of male patients
Glycoconjugates recognized by peanut agglutinin lectin in the inner acellular layer of the lamina propria of seminiferous tubules in human testes showing impaired spermatogenesis.
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BACKGROUND
The aim of this study was to evaluate the histochemical characteristics of the thickened inner acellular layer (IL) of the lamina propria specifically present in the human seminiferous tubules of testes showing impaired spermatogenesis.
METHODS
Eighteen biopsies for the investigation of
Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats.
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Dietary methionine restriction (MR) has been found to enhance longevity across many species. We hypothesized that MR might enhance longevity in part by delaying or inhibiting age-related disease processes. To this end, male Fischer 344 rats were fed control (CF, 0.86% methionine) or MR (0.17%
Nephrotoxicity of cis-diamminedichloroplatinum with or without ifosfamide in cancer treatment.
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cis-Diamminedichloroplatinum (DDP) and ifosfamide (IPP) are effective cytostatic agents with a considerable nephrotoxicity. Because of the known synergism of both drugs in animals the combination has been studied in man with disseminated testicular cancer. Nature and extent of nephrotoxicity of DDP
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