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tupistra chinensis/radang
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Antiproliferative and anti-inflammatory polyhydroxylated spirostanol saponins from Tupistra chinensis.
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Tupistra chinensis is widely distributed in southwestern China and its rhizome is a famous folk medicine for the treatment of carbuncles and pharyngitis. Its chemical identity of potent antiproliferative and anti-inflammatory constituents has been carried out in this study. Twenty-three
Antiproliferative and anti-inflammatory furostanol saponins from the rhizomes of Tupistra chinensis.
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Phytochemical investigations of the rhizome of Tupistra chinensis led to the isolation of ten new furostanol saponins along with fourteen known spirostanols. Their chemical structures were elucidated on the basis of spectroscopic and chemical methods, including IR, NMR, MS, and GC analyses. The
Total saponins of Tupistra chinensis induces apoptosis in A549 cells.
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Tupistra chinensis Baker has been used as a folk remedy in China, and it has been shown to exhibit anti-inflammation, expectorant and anti-bacterial effects. In this study, we report the cytotoxic activity of the total saponins of Tupistra chinensis Baker (TST) against several carcinoma cell lines,
[Study on the anti-endotoxin effect of saponin from Tupistra chinensis].
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OBJECTIVE
To investigate the effect of saponin from Tupistra chinensis Baker (STCB) on lethal toxicity of endotoxin in mice and explore the underlying mechanism.
METHODS
Mouse models of endotoxin-induced death and endotoximia were established by intraperitoneal administration of KM mice with
Tupistra chinensis extract attenuates murine fulminant hepatitis with multiple targets against activated T lymphocytes.
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OBJECTIVE
The extract of Tupistra chinensis (TCE) is traditionally used for the treatment of inflammatory diseases in southwestern China for hundreds of years. The present study was designed to investigate the effects of the TCE against experimental hepatitis and to illustrate its potential
A spirostanol saponin isolated from Tupistra chinensis Baker simultaneously induces apoptosis and autophagy by regulating the JNK pathway in human gastric cancer cells
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T-17, a bioactive spirostanol saponin extracted from Tupistra chinensis Baker, was previously reported with anti-inflammatory and cytotoxic activities. However, the mechanism underlying of its anti-proliferation activity remains to be elucidated. In this study, we investigated the anti-gastric
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