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Timing of Renal Replacement Therapy in the Critically Ill Patients

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Background - Optimal timing of renal replacement therapy (RRT) initiation in critically ill patients with acute kidney injury (AKI) is unknown - No consensus guides clinical practice on this issue - Conflicting results from randomized controlled trials - Lack of consistency regarding outcome; should

Lactated Ringer's Versus Normal Saline for Acute Pancreatitis

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Background: Acute pancreatitis is a common problem in the United States necessitating 275,000 hospital admissions per year, with resultant healthcare costs of approximately 2.5 billion USD annually. As numerous trials have failed to show a benefit to specific pharmacologic therapies in acute

The Artificial Kidney Initiation in Kidney Injury 2

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The timing of renal replacement therapy (RRT) in the context of severe acute kidney injury (AKI) is one the most debated issues in critical care medicine. The Artificial Kidney Initiation in Kidney Injury (AKIKI) was the first large prospective multicenter randomized trial published on this topic.

Lung Ultrasound Guided Protocol for Fluid Management for the Critically Ill Patient: a Randomized Study

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Inclusion criteria - Age 18 or older admitted to the Intensive Care Unit Exclusion criteria - Due to LUS measurement limitation: patients with known persistent pleurisy, pulmonary fibrosis or pneumectomy; - Unwillingness to participate in the study. Active arm diuretic administration algorithm -

Artificial Kidney Initiation in Kidney Injury

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Background: Acute kidney injury (AKI) is a common complication in intensive care unit (ICU) patients. Renal replacement therapy (RRT) is the major supportive treatment of AKI. Despite progress in RRT management, mortality remains high and the timing of its initiation remains open to debate when no

Safety and Efficacy Study of Intravenous Immunoglobulin to Treat Japanese Encephalitis

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Japanese encephalitis (JE) is the most important epidemic encephalitis worldwide, causing approximately 35-50,000 cases and 10-15,000 deaths annually. Half of the survivors have severe neuropsychiatric sequelae, posing a large socio-economic burden on communities that can ill afford it. JE virus

Moderate Versus Aggressive Fluids for Acute Pancreatitis

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TITLE: Moderate Versus Aggressive Fluid Therapy in Patients with Mild to Moderate Acute Pancreatitis BACKGROUND AND HYPOTHESES In the United States, acute pancreatitis results in more than 200,000 hospital admissions each year and has an associated mortality of 5%. While protease inhibitors,

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Herbal & Natural Medicine

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