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Evaluation of Effect of Topical Melatonin in Treatment of Oral Leukoplakia

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The World Health Organization (W.H.O). defines oral potentially malignant disorders (OPMDs) as "A histologically proven lesion that is associated with a significantly increased risk of malignant transformation."Oral leukoplakia is the most commonly occurring oral potentially malignant disorder.

Lycopene and Beta-carotene Metabolism in the Digestive Tract of Healthy Men

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Consumption of foods containing the carotenoids lutein, lycopene, beta-carotene, as well as vitamin E, have been associated with lower risk of developing chronic diseases including cardiovascular disease, cancer, age related macular degeneration, and cognitive decline. While the parent compounds

The Beneficial Effects of Pomegranate on Hearing of Patients Without Hemodialysis

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Pomegranate has anti-oxidative capacity. It might reduce symptoms of Alzheimer's disease, Drug-induced hepatitis, and might prevent deterioration of cardiovascular diseases and cancer progression. But, the beneficial effects of pomegranate on hearing impairment was still unclear. This study aimed to

The Potential Role of Dietary Antioxidant Capacity on Age-Related Macular Degeneration

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While being benefited from the results of previous studies, the sample size of the research was type 1 error performance α=0.05 and type 2 error performance β=0.20. The power of the test was taken as 1-β=0.80 and the power analysis was statistically made with NCCS PAS 11 program. 200 individuals

The Effect of Oral Administration of 9-cis Rich Powder of the Alga Dunaliella Bardawil on Visual Functions in Adolescent Patients With Retinitis Pigmentosa

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Retinitis pigmentosa is a genetically disease consisting of progressive retinal degeneration starting in the rods. Its prevalence is 1:4000 people and is the fourth most common blinding disease in Israel in 2004 [7% of all blindness]. The investigators treated a non-progressive form of the disease

Study of the Effects of Supplements on Eye Disease in Participants From the Age-Related Eye Disease Study

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The Age Related Eye Disease Study 2 (AREDS2) was a multicenter Phase III randomized clinical trial designed to assess the effects of oral supplementation of high doses of macular xanthophylls (lutein and zeaxanthin) and/or omega-3 LCPUFAs as a treatment for age-related macular degeneration (AMD),

The Effect of Oral Administration of 9-cis β Carotene Rich Powder of the Alga Dunaliella Bardawil

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Blood and Saliva Sample Collection for AREDS 2

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AREDS2 is a multi-center, Phase III, randomized clinical trial designed to assess the effects of oral supplementation of high doses of macular xanthophylls (lutein and zeaxanthin) and/or omega-3 long-chain polyunsaturated fatty acids (LCPUFAs) as a treatment for age-related macular degeneration

The Effect of Oral Administration of 9-cis Rich Powder of the Alga Dunaliella Bardawil on Visual Functions im Patients With Retinitis Pigmentosa

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Neptune Krill Oil (NKO™) in Early Stage Alzheimer's Disease (MNEMOSYNE)

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Alzheimer's disease (AD) is an irreversible, progressive neurodegenerative disorder, characterized by gradual cognitive deterioration, changes in behavior and personality. These symptoms are related to neurochemical changes, neural death, and the breakdown of the inter-neural connections. Loss of

Antioxidant Systems and Age-Related Macular Degeneration

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Inclusion Criteria - Age 55-80 - 70 Participants with Intermediate or Advanced AMD - 70 participants with no ocular signs of AMD - Willing to give written informed consent, make the required study visits, and follow instructions - Any race and either sex Exclusion Criteria - Current history of a

Age-Related Eye Disease Study (AREDS) Follow-Up

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The Age-Related Eye Disease Study (AREDS) Follow-Up protocol allows us to continue with the follow-up of participants who were enrolled in the clinical trial of antioxidant vitamins and zinc. The AREDS study was designed in the beginning to determine the clinical course and prognosis of age-related

Age-Related Eye Disease Study 2 (AREDS2)

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AREDS2 was a randomized, double-masked, placebo-controlled, 2x2 factorial trial evaluating the risks and benefits of adding lutein (10 mg) + zeaxanthin (2 mg), DHA (350 mg) + EPA (650 mg), or both to the AREDS formulation, which consisted of vitamins C (500 mg), vitamin E (400 international units),

Role of Antioxidants Supplementation in Chronic Pancreatitis

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INTRODUCTION Chronic pancreatitis (CP) is a progressive inflammatory disease of the pancreas accompanied by abdominal pain and in late stages, by exocrine and endocrine insufficiency. The etiology of CP include alcohol abuse, hereditary, ductal obstruction, tropical pancreatitis, systemic diseases

Physicians' Health Study II

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OBJECTIVES: Primary - To determine whether vitamin E every other day reduces the risk of developing prostate cancer in older healthy male physicians. - To determine whether daily vitamin C and/or a multivitamin reduces the risk of total cancer in these participants. - To determine whether vitamin E

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