bronchiolitis obliterans/albumin

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Rattus model utilizing selective pulmonary ischemia induces bronchiolitis obliterans organizing pneumonia.

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Bronchiolitis obliterans organizing pneumonia (BOOP), a morbid condition when associated with lung transplant and chronic lung disease, is believed to be a complication of ischemia. Our goal was to develop a simple and reliable model of lung ischemia in the Sprague-Dawley rat that would produce

Systemic uptake, albumin and hemoglobin binding of [(14)C]2,3-butanedione administered by intratracheal instillation in male Harlan Sprague Dawley rats and oropharyngeal aspiration in male B6C3F1/N mice.

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2,3-Butanedione (BD) is a reactive diketone in artificial butter flavors that is thought to cause bronchiolitis obliterans in workers in microwave popcorn manufacturing. Bronchiolitis obliterans is generally not diagnosed until irreversible damage has occurred; therefore a biomarker of early

[Concentration of alkaline phosphatase (AP) and AP/albumin ratio in bronchoalveolar lavage (BAL) for the diagnosis of interstitial lung diseases].

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As a result of several studies with different animal models there is evidence that the concentration of AP in BAL is produced in the pneumocyte II and that an increase of AP in the BAL is a marker of tissue damage. By measuring AP in the BAL of patients with interstitial lung diseases we

Perfusion and ventilation isotope lung scans in constrictive bronchiolitis obliterans. A series of three cases.

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Constrictive bronchiolitis obliterans (BO) has been defined as a syndrome of airflow limitation due to bronchiolar and peribronchiolar inflammation and fibrosis. However, chest roentgenograms are frequently normal, and alternative radiographic evaluation or other manifestations of the disease would

Factors related to the relapse of bronchiolitis obliterans organizing pneumonia.

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OBJECTIVE The purpose of this study is to determine factors, including laboratory data, related to the relapse of bronchiolitis obliterans organizing pneumonia (BOOP). METHODS Retrospective study. METHODS The medical files of Fukuoka University Hospital and Nishi Fukuoka Hospital patients from 1984

[Severe hypoxemia with orthodeoxia due to right to left shunt in idiopathic bronchiolitis obliterans organizing pneumonia].

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We report a case of BOOP with severe hypoxemia and orthodeoxia. Chest X-ray showed bilateral infiltrative pneumonia and computed tomography scan revealed consolidations on lower lobes. Diagnosis of right-to-left shunt was made on the increase of alveolar-arterial oxygen difference under FIO2 100%,

Perioperative factors associated with 1-year mortality after lung transplantation: a single-center experience in Korea.

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UNASSIGNED Most studies about the risk factors of 1-year mortality after lung transplantation were performed on non-Asians. This study aimed to evaluate the perioperative factors related to the 1-year mortality after lung transplantation in Korea. UNASSIGNED Sixty-eight consecutive patients who

Isogravitational heterogeneity of perfusion after unilateral lung transplantation.

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1. Single-photon emission computerized tomography in both an intact canine model and man has demonstrated an aspect of pulmonary perfusion to be independent of gravitational forces. 2. Using technetium 99m-labelled macroaggregated albumin single-photon emission computerized tomographic imaging, we

Respiratory failure and sepsis are the major causes of ICU admissions and mortality in survivors of lung transplants.

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OBJECTIVE To identify outcome predictors and prognostic factors in long-term survivors (> 30 days post-transplant) of single-lung and double-lung transplants on readmission to the medical ICU (MICU). METHODS Retrospective study. METHODS MICU of the Cleveland Clinic Foundation, a lung transplantation

Release of B cell-activating factor of the TNF family in bronchoalveolar lavage from Behçet's disease with pulmonary involvement.

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Pulmonary artery aneurysms, arterial and venous thrombosis, pulmonary infarction, recurrent pneumonia, bronchiolitis obliterans organized pneumonia, and pleurisy are the main features of pulmonary involvement in Behçet's disease. The objective of this study was to investigate the production of B

Pulmonary complications of combination therapy with cyclophosphamide and prednisone.

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Oral cyclophosphamide and prednisone are standard treatment for some neoplasms and necrotizing systemic vasculitis and are advocated with increasing frequency for idiopathic interstitial lung disease. During a 15-month period, we observed four cases of acute respiratory failure from Pneumocystis

Iron overload and nitric oxide-derived oxidative stress following lung transplantation.

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BACKGROUND Reactive oxygen species (ROS) may contribute to airway injury and the development of the bronchiolitis obliterans syndrome (BOS) following lung transplantation (LT). Chemically active iron released from ferritin stores and nitric oxide (NO)-derived radicals may add to the oxidative

Impairment of bronchial mucociliary clearance in long-term survivors of heart/lung and double-lung transplantation. The Paris-Sud Lung Transplant Group.

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The study objective was to investigate bronchial mucociliary clearance after heart/lung and double lung transplantation. Bronchial mucociliary clearance was measured using a noninvasive radioaerosol technique: 99mTc-labeled albumin was aerosolized using a spinning-top generator (mass median

Disruption of iron homeostasis in the lungs of transplant patients.

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BACKGROUND Oxidative stress has been proposed as a mechanism of injury underlying obliterative bronchiolitis. Catalytically reactive iron is a potential source of reactive oxygen species in transplanted tissue. Using samples acquired from surveillance bronchoalveolar lavage (BAL), we tested the

[Analysis of cells and proteins in bronchoalveolar lavage fluid].

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We studied cells and proteins in bronchoalveolar lavage fluid examined at the First Department of Internal Medicine of Shinshu University Hospital between 1990 and 1994. The samples came from 21 healthy subjects and from 216 patients with various diseases. Lymphocyte counts were abnormally high in

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