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Marijuana-induced Coronary Vasospasm and Myocardial Infarction: A Case Report and Review of Literature

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The usage of marijuana and its legalization has been growing rapidly, being abused by a wide range of age groups. Its effects on the heart are well known, but coronary artery vasospasm causing ST elevation myocardial infarction (STEMI) from Marijuana alone is rather lesser known. Herein, we report a

Smoking and cardiovascular health: a review of the epidemiology, pathogenesis, prevention and control of tobacco.

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The causal associations between cigarette smoking and human diseases are irrefutable. In this review, we focus on the epidemiological pattern of cigarette smoking on cardiovascular risk, the underlying mechanistic process of such a causal link, how to prevent premature cardiovascular morbidity and

[Acute myocardial ischemia in spontaneous coronary artery spasm].

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OBJECTIVE To discover what factors indicate spontaneous coronary artery spasms as a cause of myocardial ischaemia. METHODS In a retrospective analysis 15 of 1407 consecutive patients who had undergone coronary arteriography (six women and nine men; mean age 47 +/- 11 years) had acute ischaemia due

Coronary Vasospasm After Burn Injury: First Described Case Series of a Lethal Lesion.

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Burn injuries generate multisystem physiological derangements. The authors present a case series of three patients developing acute coronary syndrome (ACS) stemming from coronary vasospasm (CVS) over a course of 5 months. This etiology of ACS is significant as it has previously not been described in

Coronary artery spasm - Clinical features, pathogenesis and treatment.

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Coronary artery spasm (CAS) plays an important role in the pathogenesis of ischemic heart disease, including angina pectoris, myocardial infarction, and sudden death, occurring most often from midnight to early morning. CAS is prevalent among East Asians and is associated with an aldehyde

Activation of the monocytic α7 nicotinic acetylcholine receptor modulates oxidative stress and inflammation-associated development of coronary artery spasm via a p38 MAP-kinase signaling-dependent pathway.

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OBJECTIVE Smoking and high-sensitivity C-reactive protein (hs-CRP) are risk factors for coronary artery spasm (CAS), which is characterized by the increased interleukin-6 (IL-6) level and monocyte counts; however, limited data are available regarding the role of cigarette-embedded nicotine in the

Spontaneous Left Main and Right Coronary Artery Spasm in a Patient With Vasospastic Angina.

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Coronary spasm is a well-documented, though rare, condition that can mimic myocardial infarction and is usually found in only a single vessel during an event. We describe the case of a 43-year-old male with past medical history of hypertension, hyperlipidemia, tobacco abuse, and with no known

A prehospital acute coronary syndrome in a cocaine user: an unstable clinical situation.

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Chest pain is a common reason why cocaine-addicted patients call the emergency department, and acute coronary syndromes are difficult to diagnose in these situations. A 30-year-old cocaine-user patient contacts the Emergency Medical Assistance Service with constrictive chest pain. A doctor is sent

Myocardial infarction with normal coronary arteriogram: the role of ephedrine-like alkaloids.

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BACKGROUND The overwhelming majority of myocardial infarctions result from atherosclerosis, generally with superimposed coronary thrombosis. The prevalence of patients who develop myocardial infarction and in whom subsequent angiography shows normal coronary arteries is approximately 5%. Many of

A Left Main Coronary Artery Thrombus Presenting as a Non St Elevation MI.

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BACKGROUND Left main coronary artery (LMCA); thrombus with an acute myocardial infarction identified with coronary angiography is a clinically rare condition with an extremely high mortality rate. We present a case of LMCA thrombus that presented as a non-ST elevation myocardial infarction

Acute inferior ST-elevation myocardial infarction due to delirium tremens: a case report.

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Delirium tremens is a severe form of alcohol withdrawal syndrome. Literature documenting acute coronary events in the setting of alcohol withdrawal remains scarce. An accepted hypothesis for the underlying process is focused on the hyperadrenergic state that leads to coronary vasospasm

Rho-kinase is an important therapeutic target in cardiovascular medicine.

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Rho-kinase has been identified as one of the effectors of the small GTP-binding protein Rho. Accumulating evidence has demonstrated that Rho/Rho-kinase pathway plays an important role in various cellular functions, not only in vascular smooth muscle cell (VSMC) contraction but also in actin

Hemodynamic and vascular effects of active and passive smoking.

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Epidemiologic studies suggest that active and passive exposure to tobacco smoke is an important cause of cardiovascular morbidity and mortality. Numerous clinical studies have demonstrated that cigarette smoking causes coronary vasoconstriction, an increase in coronary vascular resistance, and a

The Bezold-Jarisch reflex. A historical perspective of cardiopulmonary reflexes.

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The Bezold-Jarisch reflex is an eponym for a triad of responses (apnea, bradycardia, and hypotension) following intravenous injection of veratrum alkaloids in experimental animals. The observation was first reported in 1867 by von Bezold and Hirt, and confirmed in 1938-1940 by Jarisch. The triad

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