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gastritis/nausea

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15 niðurstöður

Thieno[3,2-b]pyridine derivatives

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FIELD OF THE INVENTION The present invention relates to novel thieno[3,2-b]pyridine derivative useful as pharmaceutical agents. More specifically, the present invention relates to novel thieno[3,2-b]pyridine derivatives, the pharmaceutically acceptable salts thereof and the solvates thereof,

Deuterium-enriched pyridinonecarboxamides and derivatives

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SUMMARY OF THE INVENTION The present invention is concerned with deuterium-enriched pyridinone carboxamides and derivatives thereof of formula I, ##STR00002## Wherein, R.sub.1 and R.sub.2 are independently, H, D (deuterium with enrichment of 1%-100%), F, Cl, CD.sub.3 (methyl-d.sub.3),

Deuterium-enriched pyridinonecarboxamides and derivatives

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SUMMARY OF THE INVENTION The present invention is concerned with deuterium-enriched pyridinonecarboxamides and derivatives thereof of formula 1, ##STR00002## Wherein, R.sub.1 and R.sub.2 are independently, H, D (deuterium with enrichment of 1%-100%), F, Cl, CD.sub.3 (methyl-d.sub.3),

Material and methods for the treatment of gastro-intestinal disorders

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FIELD The present disclosure relates to bulk compositions and pharmaceutical compositions comprising a trihydrate form of (3S, 4R, 3'R)-6-[4-(4-amino-5-chloro-2-methoxy-benzoylamino)-3-methoxy-piperidin-1- -yl]-hexanoic acid 1-azabicyclo[2.2.2]oct-3'-yl ester di-hydrochloride salt, and methods of

Thienopyridinone compounds and methods of treatment

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FIELD OF THE INVENTION The invention generally relates to the field of serotonin (5-hydroxytryptamine, or 5-HT) receptor modulators, e.g., agonists, partial agonists, inverse agonists, antagonists, and more particularly to new thienopyridinone compounds, the synthesis and use of these compounds and

Thienopyridinone compounds and methods of treatment

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FIELD OF THE INVENTION The invention generally relates to the field of serotonin (5-hydroxytryptamine, or 5-HT) receptor modulators, e.g., agonists, partial agonists, inverse agonists, antagonists, and more particularly to new thienopyridinone compounds, the synthesis and use of these compounds and

Synthesis of thienopyridinone compounds and related intermediates

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FIELD OF THE INVENTION The invention generally relates to the field of serotonin (5-hydroxytryptamine, or 5-HT) receptor modulators, e.g., agonists, partial agonists, inverse agonists, antagonists, and more particularly to new thienopyridinone compounds, the synthesis and use of these compounds and

Aromatic amides of heterocyclic compounds and therapeutic compositions containing same

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SUMMARY OF THE INVENTION According to our invention, in its broadest aspect, we provide a compound corresponding to the general formula (I): ##STR1## in which: R is a lower (C.sub.1 -C.sub.6) alkoxy or alkenoxy; R.sub.1 and R.sub.2, which may be the same or different, are selected from hydrogen,

Chromane substituted benzimidazole derivatives

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BACKGROUND OF THE INVENTION This invention relates to chromane substituted benzimidazole derivatives. These compounds have selective acid pump inhibitory activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for

Chromane substituted benzimidazole derivatives as acid pump antagonists

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BACKGROUND OF THE INVENTION This invention relates to chromane substituted benzimidazole derivatives. These compounds have selective acid pump inhibitory activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for

Benzimidazole derivatives as selective acid pump inhibitors

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BACKGROUND OF THE INVENTION This invention relates to tricyclic compounds. These compounds have selective acid pump inhibitory activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment of disease

Anti-psychotic (cycloalkenylalkylpiperidino) benzamides

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SUMMARY OF THE INVENTION According to one aspect of our invention, we provide compounds of the general formula ##STR1## wherein R represents a lower alkoxy or lower alkenyloxy group; R.sup.1 and R.sup.2, which may be the same or different, each represent a hydrogen or halogen atom, or a

Substituted benzoylaminothiazole derivatives and drugs containing the same

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TECHNICAL FIELD The present invention relates to a novel benzoylaminothiazole derivative having improving effects on the dysmotility in the gastrointestinal tract, a medicament containing the derivative and an intermediate for preparing said compound. BACKGROUND ART As a therapeutic agent for

Cinnoline-3-carboxylic acid derivatives

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FIELD OF THE INVENTION This invention relates to a cinnoline derivative which is pharmaceutically useful as an antagonist against serotonin 5-HT.sub.3 receptor, its pharmaceutically acceptable salts, its N-oxide derivatives or solvates thereof, and pharmaceutical compositions containing the

Cinnoline-3-carboxylic acid derivatives

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FIELD OF THE INVENTION This invention relates to a cinnoline derivative which is pharmaceutically useful as an antagonist against serotonin 5-HT.sub.3 receptor, its pharmaceutically acceptable salts, its N-oxide derivatives or solvates thereof, and pharmaceutical compositions containing the
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