hexasaccharide/blæðing

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Antihemostatic activity of heparin disaccharides and oligosaccharides obtained by chemical and enzymatic fragmentation: reversal of the hemorrhagic activity by ATP and myosin.

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Heparin and its fragments, namely, trisulfated disaccharide, pentasulfated tetrasaccharide, octasulfated hexasaccharide and an oligosaccharide (M.W. 6,300) prepared by enzymatic fragmentation and an oligosaccharide (M.W. 4,500) prepared by chemical fragmentation are potent inhibitors of skin

Synthesis of 3-O-Sulfated Oligosaccharides to Understand the Relationship between Structures and Functions of Heparan Sulfate.

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The sulfation at the 3-OH position of glucosamine is an important modification in forming structural domains for heparan sulfate to enable its biological functions. Seven 3-O-sulfotransferase isoforms in the human genome are involved in the biosynthesis of 3-O-sulfated heparan sulfate. As a rare

SR123781A, a synthetic heparin mimetic.

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SR123781A, a synthetic hexadecasaccharide comprising an antithrombin (AT) binding domain, a thrombin binding domain, and a neutral methylated hexasaccharide sequence, was obtained from glucose through a convergent synthesis. SR123781A showed high affinity for human AT (Kd = 58 +/- 22 nM) and was a

Changes in intrinsic circular dichroism of several homogeneous anti-type 3 pneumococcal antibodies on binding of a small hapten.

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Three homogeneous antibodies against the capsular polysaccharide of Type III pneumococci of similar specificities and affinities were purified from a single bleeding of an individual rabbit and fractionated by isoelectric focusing. A comparison of the circular dichroic spectra of the three

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Herbal & Natural Medicine

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