optimel manuka eyedrops 10 ml used as directed in a CAC (Conjunctival allergen challenge) study

sterile normal saline eyedrops used as directed in a CAC (conjunctival allergen challenge) study

Allergic Conjunctivitis

manuka eyedrops applied to the ocular surface

Manuka honey

Toyos Clinic

Manuka Eye Droops for Treatment of Allergy

A Phase 4 Study to Assess the Clinical Efficacy and Safety of Manuka Eye Drops for Treatment of Allergy

on a scale from 0-100 where 0 =no itching and 100=maximal itching subtracted scores measured for placebo treatments at visits 3B, 4 and 5

on a scale from 0-100 where 0=no hyperemia and 100=maximal hyperemia subtracted scores from placebo treatments at visits 3B, 4 and 5

If requested, data records without identifying patient information could be shared

randomized, double-blind placebo controlled

medications will be covered by blank labels

Manuka Honey will be placed in the sockets of the extracted third molars in this group

No any special material will be placed in the sockets of the extracted third molars in this group

Surgical Extraction of Impacted Third Molars

This material is going to be placed into the sockets of the extracted third molars in the experimental group

Manuka Honey

Department of Oral and Maxillofacial Surgery, University of Damascus Dental School

The Use of Manuka Honey to Improve Healing After Third Molars Surgery

The Effect of Topical Application of Manuka Honey on Healing After Extraction of Impacted Lower Third Molars: A Split-Mouth Design Randomized Controlled Trial

Postoperative Symptom Severity (PoSSe) Scale will be used for this variable. The patient will be asked to fill in a questionnaire on the 7th day following surgery. This questionnaire is used to assess postoperative discomfort in patients who have third molars extracted. PoSSe Scale consists of 7 sub-scales that investigate the patient's ability to enjoy food; speak properly; perceive altered sensations, appearance, pain, and sickness; and interference with daily activities.

In order to assess facial swelling, the distances between the labial commissure and the tragus, and between the lateral canthus and the gonion will be measured.
The change between 3 days and before surgery will give an idea about the amount of swelling that occurred following surgery.
Between 3 days and 7 days will give an idea about the change that occurred in this period.

Mouth opening range will be assessed by measuring the distance between the upper and lower incisors using a vernier caliper when the patient is asked to open his/her mouth as much as possible.
The presence of limited opening of the mouth is an indication of trismus.

using a Visual Analog Scale of Faces (VASoF).

The presence of a dry socket condition will be checked out at two time points.

This will be assessed using Cone-beam computed tomography (CBCT) images. Hounsfield Units will be used to quantify bone density and quality.

This will be assessed using panoramic radiographs

Damascus University

Study patients diagnosed with acute pouchitis after bowel surgery for ulcerative colitis will perform manuka honey enemas twice a day for 30 days.

Pouchitis

Study patients diagnosed with acute pouchitis will perform manuka honey enemas twice a day for 30 days.

Manuka honey enema

Saint Paul's Hospital

To Determine the Effect of Honey Enema in the Treatment of Patients With Acute Pouchitis

To Determine the Effect of Honey Enema in the Treatment of Patients With Acute Pouchitis (Pilot Study)

PDAI score is a criterion for defining pouchitis. A PDAI score will be calculated from a proctoscopy assessment before treatment. Within two weeks after the treatment, another proctoscopy will be performed to determine the post-treatment PDAI score to see if there is a decrease in PDAI score for the study patients.

includes stool frequency (no different, 1-2 stools/day > postoperative usual, 3 or more stools/day > postoperative usual), rectal bleeding (none or rare or present daily), fecal urgency or abdominal cramps (none, occasional or usual), presence of fever (temperature >37.8° C), abdominal pain (no, occasional or usual) and readmission to hospital for any reason.

leptospermum scoparium/andoxunarefni

Manuka Eye Droops for Treatment of Allergy

The Use of Manuka Honey to Improve Healing After Third Molars Surgery

To Determine the Effect of Honey Enema in the Treatment of Patients With Acute Pouchitis

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