osteogenesis imperfecta/phosphatase

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Total body bone mineral and tartrate-resistant acid phosphatase levels in type I and III osteogenesis imperfecta.

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Serum tartrate-resistant acid phosphatase (TRAP) and total body bone mineral content (TBBM) were determined in a group of 16 children with osteogenesis imperfecta (OI) aged 5-14 years, 9 of whom suffered from type I and 7 from type III OI. TRAP and TBBM were also determined in a group of 26 normal

Enzyme histochemical localisation of alkaline phosphatase activity in osteogenesis imperfecta bone and growth plate: a preliminary study.

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At the ultrastructural level alkaline phosphatase has been studied in calcifying cartilage but not in bone. The aim of this study was to assess if there is an osteoblast dysfunction in Osteogenesis Imperfecta (OI) with respect to alkaline phosphatase activity. Specimens from three OI type II foetal

Fragilitas Ossium in a Family showing both Thickening and Rarefaction of Bones, Relative Lymphocytosis and raised Serum Phosphatase with Absence of Blue Sclerotics and Otosclerosis.

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Decrease of serum alkaline phosphatase after three cycles of pamidronate disodium in children with severe osteogenesis imperfecta.

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[Alkaline phosphatase and its isoenzyme activity of the blood in osteogenesis imperfecta before and during treatment with calcitonin].

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Normal serum acid phosphatase levels in osteogenesis imperfecta.

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Serum acid phosphatase in osteogenesis imperfecta.

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[Acid phosphatases in congenital fragilitas ossium].

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Study of the Determinants of Vitamin D Status in Pediatric Patients With Osteogenesis Imperfecta.

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Vitamin D is essential to the development and maintenance of the skeleton, especially for children with bone disorders such as osteogenesis imperfecta (OI). We evaluated serum 25-hydroxyvitamin D (25-OHD) levels to assess the relationship between determinants of vitamin D status in pediatric

[Callus luxurians in osteogenesis imperfecta].

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A case is introduced with osteogenesis imperfecta, suffered from left femoral fracture and a consecutive hypertrophic callus formation, with extreme swelling on the thigh. Concerning the laboratory tests the only significant difference was the elevation in alkaline phosphatase activity and a

Increased bone resorption with decreased activity and increased recruitment of osteoblasts in osteogenesis imperfecta type I.

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An iliac bone biopsy from an adult male, 58 years of age, with osteogenesis imperfecta type I was studied by bone histomorphometry after double-fluorescence labeling with tetracycline. Low bone mineral density (BMD) of the radius, measured by dual-energy X-ray absorptiometry (DXA) was associated

Vertebral Fracture Assessment (VFA) for monitoring vertebral reshaping in children and adolescents with Osteogenesis Imperfecta treated with intravenous neridronate

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Purpose: The study was aimed at monitoring vertebral bodies changes with the use of Vertebral Fracture Assessment (VFA) in children and adolescents affected by osteogenesis imperfecta (OI) during treatment with intravenous

Collagen-derived markers of bone metabolism in osteogenesis imperfecta.

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Markers of bone formation [C-terminal and N-terminal propeptides of procollagen I (PICP, PINP), osteocalcin and alkaline phosphatase] and bone resorption [C-terminal cross-linked telopeptide of collagen I (ICTP) and hydroxypyridinium cross-links, pyridinoline (Pyr) and deoxypyridinoline (Dpyr)] were

Isolation and characterization of bone cells from a patient with osteogenesis imperfecta type 1b.

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The metabolic defect(s) in bone cells which manifests itself in the disease osteogenesis imperfecta (OI) type 1 is not known. Since this form of the disease displays both a variable tissue involvement and the possibility of remission it is difficult to attribute its expression to a primary mutation

Cyclic pamidronate infusion improves bone mineralisation and reduces fracture incidence in osteogenesis imperfecta.

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A prospective open study was performed to determine the efficacy and safety of pamidronate in improving bone mineralisation and reducing fracture incidence in osteogenesis imperfecta (OI). Intravenous pamidronate was administered at 1.5 mg/kg bi-monthly to six children with OI, over 12-23 months.

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