Subjects would introduce 5 different groups of FODMAPs in a blinded fashion (random order, 1 week on, one week off) while remaining on an otherwise low FODMAP diet while monitoring their IBS symptoms.

Irritable Bowel Syndrome

After 2 weeks on a low FODMAP diet, subject will undergo a reintroduction period. 5 different FODMAPs will be reintroduced (1 week at a time, followed by 1 week washout) in a blinded, randomized fashion.

FODMAP

University of Michigan

Diet Reintroduction Study in Irritable Bowel Syndrome

Charting a Course to a Less Restrictive Diet for IBS

Daily score (0-10) for abdominal pain will be recorded. This will be averaged and compared to the baseline and run-in periods

Daily score (0-10) for bloating will be recorded. This will be averaged and compared to the baseline and run-in periods

Daily stool consistency score will be recorded. This will be averaged and compared to the baseline and run-in periods

Daily number of stools will be recorded. This will be averaged and compared to the baseline and run-in periods

Daily score (0-10) for stool urgency will be recorded. This will be averaged and compared to the baseline and run-in periods

Daily score (0-10) for fatigue will be recorded. This will be averaged and compared to the baseline and run-in periods

Daily score (0-10) for sleep quality will be recorded. This will be averaged and compared to the baseline and run-in periods

Shanti Eswaran

Clinical Assistant Professor

Food items will be blindly reintroduced, and symptoms will be measured.

Participants blinded to randomization of order of reintroduction; Investigators blinded to order of reintroduction

Pectin （Andeli Ltd. Yantai, China）, 24g/d for six weeks

Pectin

maltodextrin

Effects of Pectin Supplementation in Diarrhea-predominant Irritable Bowel Syndrome

Therapeutic Effects of Pectin Supplementation in Patients With Diarrhea-predominant Irritable Bowel Syndrome

change from baseline in stool frequency, faecal form (Bristol stool scale) and clinical symptoms score (7-point Likert scale) at six weeks

pectin/niðurgangur

Diet Reintroduction Study in Irritable Bowel Syndrome

Effects of Pectin Supplementation in Diarrhea-predominant Irritable Bowel Syndrome

Heillasta gagnagrunnur lækningajurtanna sem studdur er af vísindum