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(E,E)-3-Methyl-2,5-bis-(4-methyl-benzyl-idene)cyclo-penta-none: synthesis, characterization, Hirshfeld surface analysis and anti-bacterial activity.

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The title compound, (E,E)-3-methyl-2,5-bis-(4-methyl-benzyl-idene)cyclo-penta-none (MBMCP), C₂₂H₂₂O, was obtained by Claisen-Schmidt condensation of 4-methyl-benzaldehyde with 3-methyl-cyclo-penta-none in good yield. The structure of MBMCP was studied using UV,

Novel Phosphorylated Penta-1,4-dien-3-one Derivatives: Design, Synthesis, and Biological Activity.

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A series of novel phosphorylated penta-1,4-dien-3-one derivatives were designed and synthesized. The structures of all title compounds were determined by ¹H-NMR, ¹³C-NMR, ³¹P-NMR, and high-resolution mass spectrometry (HRMS). Bioassay results showed that several of the title

The acute toxicity of penta-, hexa-, and heptachlorohydroxydiphenyl ethers in mice.

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The acute intraperitoneal LD50 values of various hydroxychlorodiphenyl ethers (HO-ClX-DPEs; X = 5-7) in mice have been determined. The acute toxicities observed were on the order of, or slightly less than, that observed previously for 2-hydroxy-2',4,4'-trichlorodiphenyl ether (2-HO-Cl3-DPE; Irgasan

Bis[(2R,6S)-4-(5-amino-3-carb-oxy-1-cyclo-propyl-6,8-difluoro-4-oxo-1,4-dihydro-quinolin-7-yl)-2,6-dimethyl-piperazin-1-ium] sulfate penta-hydrate.

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The title compound, C(19)H(23)F(2)N(4)O(3) (+)·0.5SO(4) (2-)·2.5H(2)O, an anti-bacterial fluoro-quinolone, crystallized as a racemic twin (major twin component = 0.633) in the chiral space group P1. The asymmetric unit contains two sparfloxacinium cations, one sulfate anion and five mol-ecules of

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Herbal & Natural Medicine

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