porphyrin/krabbamein

Krækjan er vistuð á klemmuspjaldið

Veldu tegund tegund

Bls 1 frá 902 niðurstöður

In Situ Photocatalysis of TiO-porphyrin Encapsulated Nanosystem for Highly Efficient Oxidative Damage against Hypoxic Tumors.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

Reactive oxygen species (ROS)-mediated cell apoptosis has been a significant strategy for tumor oxidative damage, while tumor hypoxia is a major bottleneck for efficiency. Here, a novel TiO-porphyrin nanosystem (FA-TiOPs) is designed by encapsulating TiO-porphyrin (TiOP) in folate-liposome. The

Porphyrin-Based Nanomedicines for Cancer Treatment.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

As unique molecules with both therapeutic and diagnostic properties, porphyrin derivatives have been extensively employed for cancer treatment. Porphyrins not only show powerful phototherapeutic effects (photodynamic and photothermal therapies), but also exhibit excellent imaging capacities, such as

Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

BACKGROUND Porphyrin TMPyP4 (P4) and its C14H28-alkyl derivative (C14) are G-quadruplex binders and singlet oxygen (1O2) generators. In contrast, TMPyP2 (P2) produces 1O2 but it is not a G-quadruplex binder. As their photosensitizing activity is currently undefined, we report in this study their

Site-directed photoproteolysis of 8-oxoguanine DNA glycosylase 1 (OGG1) by specific porphyrin-protein probe conjugates: a strategy to improve the effectiveness of photodynamic therapy for cancer.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

The specific light-induced, non-enzymatic photolysis of mOGG1 by porphyrin-conjugated or rose bengal-conjugated streptavidin and porphyrin-conjugated or rose bengal-conjugated first specific or secondary anti-IgG antibodies is reported. The porphyrin chlorin e6 and rose bengal were conjugated to

Cell death mechanistic study of photodynamic therapy against breast cancer cells utilizing liposomal delivery of 5,10,15,20-tetrakis(benzo[b]thiophene) porphyrin.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

5,10,15,20-Tetrakis(benzo[b]thiophene) porphyrin (BTP) is a newly synthesized hydrophobic photosensitizer with fluorescence quantum yield in toluene: ΦF=0.062. Previously, its limitations in solubility had hindered scientific experimentation regarding its photodynamic effects on cancer cells. By

Tumor targeting HPMA-porphyrin-99mTc copolymer molecular imaging agent.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

Porphyrins typically show preferential uptake and retention by tumor tissues via receptor-mediated endocytosis of low-density lipoproteins. To investigate the relative importance of active and passive targeting strategies, the synthesis, characterization, in vitro uptake, and in vivo biodistribution

Tumor-localizing activity of porphyrin and its affinity to LDL, transferrin.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

We spectrochemically analyzed 12 Ga-Metal porphyrins (Ga-Cn-P) with different degrees of hydrophobicity, and observed a close association between the in vivo Ga-Cn-P localization in the tumor and its affinity to transferrin and LDL. Image analysis of tumors with 99m-Tc-STA-R12, a

Ruthenium porphyrin compounds for photodynamic therapy of cancer.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

Five 5,10,15,20-tetra(4-pyridyl)porphyrin (TPP) areneruthenium(II) derivatives and a p-cymeneosmium and two pentamethylcyclopentadienyliridium and -rhodium analogues were prepared and characterized as potential photosensitizing chemotherapeutic agents. The biological effects of all these derivatives

Biologic evaluation of a novel 188Re-labeled porphyrin in mice tumor model.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

The aim of this study was to develop a (188)Re-labeled porphyrin-based tumor-specific agent and to evaluate its biologic behavior, including tumor-regressing effectiveness, in mouse tumor models for possible use in achieving targeted cancer radiotherapy. (188)Re was obtained from an

A novel 177Lu-labeled porphyrin for possible use in targeted tumor therapy.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

BACKGROUND Porphyrin and its derivatives exhibit inherent affinity for localization in tumors. Hence, porphyrin derivatives radiolabeled with suitable therapeutic radionuclides could be envisaged as potential agents for targeted tumor therapy. In this direction, a water-soluble porphyrin derivative,

109Pd labeled 5,10,15,20-tetrakis[4-carboxymethyleneoxyphenyl]porphyrin: a potential agent for targeted tumor therapy.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

OBJECTIVE Radiolabeled porphyrin derivatives could be envisaged as potential agents for targeted tumor therapy owing to the inherent tumor accumulation property exhibited by porphyrins. However, to achieve adequately high tumor accumulation and retention therein along with fast clearance from all

Combination of porphyrins and DNA-alkylation agents: synthesis and tumor cell apoptosis induction.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

A series of porphyrin-DNA cross-linking conjugates were synthesized. Their cytotoxicities to tumor cells were tested using MTT assays first. Then, HeLa cell apoptosis induced by these cationic porphyrins under the light was examined by laser confocal microscopy, flow cytometric analysis, and further

Synthetic porphyrins as tumour-localizing agents.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

A series of radioactively labelled porphyrin analogues have been synthesized and compared for tissue distribution and tumour uptake against 67Ga in the same tumour-mouse system. The compounds were: 14C-ms-tetraphenylporphine sulphonate (14C-TPPS), 35S-ms-tetraphenylporphine sulphonate (TPP35S),

Tumour-localizing and -photosensitising properties of meso-tetra(4-nido-carboranylphenyl)porphyrin (H2TCP).

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

A water-soluble meso-substituted porphyrin (H(2)TCP) bearing 36 boron atoms, which appeared to be an efficient photodynamic sensitiser (singlet oxygen quantum yield=0.44), was studied for its accumulation by murine melanotic melanoma cells (B16F1). The amount of H(2)TCP in the cells increased with

Synthesis and biologic evaluation of I-123-labeled porphyrin derivative as a potential tumor-imaging agent.

Aðeins skráðir notendur geta þýtt greinar

Skráðu þig / skráðu þig

5-(3-(3-[(123)I]iodoallyloxy)phenyl)-10,15,20-tris-(3-carboxymethoxyphenyl)porphyrin ([ (123)I]2) was prepared for biologic evaluation in a B16-F10 tumor model to examine its potential as an imaging agent. The I-123-labeled porphyrin [(123)I]2 was purified by reverse-phase high-performance liquid

Fyrri
1
2
3
4
5
6
...
60
61
Næst

Skráðu þig á
facebook síðu okkar

Herbal & Natural Medicine

Heillasta gagnagrunnur lækningajurtanna sem studdur er af vísindum

Virkar á 55 tungumálum
Jurtalækningar studdir af vísindum
Jurtaviðurkenning eftir ímynd
Gagnvirkt GPS kort - merktu jurtir á staðsetningu (kemur fljótlega)
Lestu vísindarit sem tengjast leit þinni
Leitaðu að lækningajurtum eftir áhrifum þeirra
Skipuleggðu áhugamál þitt og vertu vakandi með fréttarannsóknum, klínískum rannsóknum og einkaleyfum

Sláðu inn einkenni eða sjúkdóm og lestu um jurtir sem gætu hjálpað, sláðu jurt og sjáðu sjúkdóma og einkenni sem hún er notuð við.
* Allar upplýsingar eru byggðar á birtum vísindarannsóknum