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[Treatment of migraine attacks].

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The authors have presented a review of the main controlled studies on drug treatment for the management of migraine attacks: non-steroidal anti-inflammatory drugs (NSAIDs), rye ergot derivatives, and the recently commercialized triptan group of drugs. An overview is provided of their specific

Bioactives in Commonly Consumed Cereal Grains: Implications for Oxidative Stress and Inflammation.

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Oxidative stress and inflammation are closely linked to various chronic diseases. Thus, targeting this axis of oxidative stress and inflammation is a particularly interesting area of study for reducing the risk of chronic diseases, including, but not limited to, metabolic disorders, cancer,

Blueberry husks, rye bran and multi-strain probiotics affect the severity of colitis induced by dextran sulphate sodium.

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OBJECTIVE The enteric microbiota is a pivotal factor in the development of intestinal inflammation in humans but probiotics, dietary fibres and phytochemicals can have anti-inflammatory effects. The aim of this study was to evaluate the therapeutic effect of multi-strain probiotics and two

[Inhibition of arachidonic acid cascade by extract of rye pollen].

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A standardized extract mainly from rye pollen (Cernilton N) was tested in vitro on the inhibition of prostaglandin and leukotrien synthesis. The determination of the prostaglandin and leukotrien synthesis from labelled arachidonic acid was done in microsomes of ram seminal vesicles resp. in rat

Inhibition of inflammatory signaling pathways in 3T3-L1 adipocytes by apolipoprotein A-I.

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Activation of inflammatory signaling pathways links obesity with metabolic disorders. TLR4-mediated activation of MAPKs and NF-κB are 2 such pathways implicated in obesity-induced inflammation. Apolipoprotein A-I (apoA-I) exerts anti-inflammatory effects on adipocytes by effluxing cholesterol from

Oncostatin M synergises with house dust mite proteases to induce the production of PGE(2) from cultured lung epithelial cells.

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The release of PGE(2) and nitric oxide (NO) from the respiratory epithelium may act to dampen inflammation. In other tissues, oncostatin M (OSM), a potent inducer of epithelial antiproteases, has also been shown to interact with IL-1beta to stimulate PGE(2) release. However, whether OSM interacts

Immunological Investigation for the Presence of Lunasin, a Chemopreventive Soybean Peptide, in the Seeds of Diverse Plants.

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Lunasin, a 44 amino acid soybean bioactive peptide, exhibits anticancer and anti-inflammatory properties. All soybean varieties that have been examined contain lunasin. It has also been reported in a few other plant species including amaranth, black nightshade, wheat, barley, rye, and triticale.

Nutraceutical treatment and prevention of benign prostatic hyperplasia and prostate cancer.

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During the last years, pharmaceutical innovations in primary care are dramatically less frequent and will be even more rare in the next future. In this context, preclinical and clinical research oriented their interest toward natural compounds efficacy and safety, supporting the development of a new

In vitro prebiotic potential of agricultural by-products on intestinal fermentation, gut barrier and inflammatory status of piglets.

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The inclusion of fibre-rich ingredients in diets is one possible strategy to enhance intestinal fermentation and positively impact gut ecology, barrier and immunity. Nowadays, inulin-type fructans are used as prebiotics in the feed of piglet's to manipulate gut ecology for health purposes. Likewise,

Oats in healthy gluten-free and regular diets: A perspective.

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During the 20th century, the economic position of oats (Avena sativa L.) decreased strongly in favour of higher yielding crops including winter wheat and maize. Presently, oat represents only ~1.3% of the total world grain production, and its production system is fragmented. Nonetheless, current

Critical study of crop-derived biochars for soil amendment and pharmaceutical ecotoxicity reduction.

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In this study, biochars (BCs) produced from crops (straw and seeds) were tested for the applicability as additive to soils. The effect on pH, water capacity and cation exchange capacity of soil were tested. The ability for the sorption of pharmaceuticals (beta-blockers, anti-inflammatory drugs,

Multi-omics analysis reveals the influence of genetic and environmental risk factors on developing gut microbiota in infants at risk of celiac disease

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Background: Celiac disease (CD) is an autoimmune digestive disorder that occurs in genetically susceptible individuals in response to ingesting gluten, a protein found in wheat, rye, and barley. Research shows that genetic predisposition

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