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Preventive and therapeutic potential of peptides from cereals against cancer.

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Epidemiological studies have shown that regular consumption of food based on whole-grain cereals and their products is associated with reduced risks of various types of degenerative chronic diseases. Food proteins are considered an important source of nutraceutical peptides and amino acids that can

Plasma levels of alkylresorcinols and incidence of endometrial cancer.

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A high intake of whole-grain foods may protect against endometrial cancer, but the existing literature is both limited and inconsistent. A significant reason for the inconsistent evidence could be methodological problems regarding accurate assessment of whole-grain intake. Alkylresorcinol (AR) has

[Phytoestrogen and cancer prevention].

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Phytoestrogens are defined to be plant chemicals that modify estrogenic effects in the body by binding to the estrogen receptors in mammals. Isoflavones, coumestane, lignan, and prenylflavones are examples of these, with isoflavones from soy foods and lignans from rye being a major dietary

Effects of phytoestrogen extracts isolated from rye, green and yellow pea seeds on hormone production and proliferation of trophoblast tumor cells Jeg3.

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BACKGROUND Phytoestrogens are a diverse group of non-steroidal plant compounds. Because they have chemical structures similar to estrogens they are able to bind on estrogen receptors in humans. OBJECTIVE In this study, we tested the effects of crude phytoestrogen extracts from rye (Secale cereale),

[Effect of the lipopolysaccharide-protein complex of Pseudomonas syringae PV. atrofaciens on the process of tumor formation caused by Agrobacterium tumefaciens].

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It has been found that the agent of bacterial spotting of rye P. syringae pv. atrofaciens 8281 has no antagonistic action on the strains 9052 and 9054 of Agrobacterium tumefaciens--the agent of crown gall tumor. Lipopolysaccharide-protein complex of P. syringae pv. atrofaciens 8281 when added to the

Serum enterolactone and risk of breast cancer: a case-control study in eastern Finland.

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Phytoestrogens have been linked to a risk of breast cancer. The main phytoestrogens in the Finnish diet are lignans, and enterolactone is quantitatively the most important circulating lignan. The purpose of this study was to examine the association between serum enterolactone and risk of breast

[Phytotherapy of benign prostate syndrome and prostate cancer: better than placebo].

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In some countries plant extracts have belonged to the most popular drugs for the treatment of the benign prostatic syndrome (BPS) for decades; however, only few of the large number of published studies meet the criteria of the WHO benign prostatic hyperplasia (BPH) consensus conference. The few

[Second neoplasms as a late complication of the treatment of Hodgkin's disease].

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OBJECTIVE To determine the incidence of a second malignancy in patients with Hodgkin's disease (HD) diagnosed and treated in the same hospital. METHODS A retrospective study was performed on 99 patients diagnosed and treated for HD in the Hospital San Carlos, in Madrid, between January 1976 and

Randomised controlled short-term intervention pilot study on rye bran bread in prostate cancer.

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The short-term effects of rye bran bread intake in prostate cancer were investigated. Ten men with conservatively treated prostate cancer were randomised to a daily supplement of 295 g of rye bran bread and eight men to 275 g of wheat bread (control) with similar fibre content for three weeks. Blood

Rye bran diet increases epithelial cell apoptosis and decreases epithelial cell volume in TRAMP (transgenic adenocarcinoma of the mouse prostate) tumors.

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A rye bran diet has been suggested to retard prostate cancer growth and increase tumor cell apoptosis in animal models and in men with prostate cancer. Transgenic mice designed to develop prostate cancer (transgenic adenocarcinoma of the mouse prostate, TRAMP) were therefore treated with a rye bran

Rye bread consumption in early life and reduced risk of advanced prostate cancer.

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OBJECTIVE To determine whether consumption of whole-grain rye bread, oatmeal, and whole-wheat bread, during different periods of life, is associated with risk of prostate cancer (PCa). METHODS From 2002 to 2006, 2,268 men, aged 67-96 years, reported their dietary habits in the AGES-Reykjavik cohort

Plasma enterolactone or intestinal Bifidobacterium levels do not explain adenoma formation in multiple intestinal neoplasia (Min) mice fed with two different types of rye-bran fractions.

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The study was designed to evaluate whether two types of rye-bran fractions result in distinct bifidogenic effect or enterolactone production in multiple intestinal neoplasia (Min) mice and whether these parameters are associated with intestinal tumorigenesis in this animal model. The experimental

Reproducibility of plasma alkylresorcinols during a 6-week rye intervention study in men with prostate cancer.

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Alkylresorcinols (AR), phenolic lipids exclusively present in the outer parts of wheat and rye grains, have been proposed as concentration biomarkers of whole-grain wheat and rye intake. A key feature of a good biomarker is high reproducibility, which indicates how accurately a single sample

Alkylresorcinol metabolites in urine and plasma as potential biomarkers of rye and wheat fiber consumption in prostate cancer patients and controls.

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Alkylresorcinols (ARs) are phytochemicals mainly associated with rye/wheat bran. Plasma ARs and their plasma and urine metabolites are considered as biomarkers for whole-grain rye/wheat intake. However ARs metabolite day and night variations have not been studied in prostate cancer patients yet. We

Effects of soy or rye supplementation of high-fat diets on colon tumour development in azoxymethane-treated rats.

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Evidence is accumulating that a diet high in plant-derived foods may be protective against cancer. One class of plant component under increasing investigation is the phytoestrogens of which there are two main groups: the isoflavones, found mainly in soy products, and the lignans, which are more

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