trigeminal neuralgia/kalín

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Familial trigeminal neuralgia - a systematic clinical study with a genomic screen of the neuronal electrogenisome.

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This cross-sectional study examined, for the first time, a large cohort of patients with trigeminal neuralgia, to ascertain the occurrence of familial cases, providing a systematic description of clinical features of familial disease. Since there is evidence linking hyperexcitability

[Changes in voltage-gated potassium currents in the trigeminal neurons after a chronic constriction of infraorbital nerve.].

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The purpose of this study was to establish a model of trigeminal neuralgia (TN) through an approach from lower edge of cheekbone and to observe the functional changes in the voltage-gated potassium currents in the cultured trigeminal ganglion (TG) neurons. Thirty Sprague-Dawley male rats were

Evaluation of biochemical variables in patients with trigeminal neuralgia.

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The aim of this study was to evaluate the calcium, sodium, potassium, serum iron, vitamin B12, and albumin concentrations, and alkaline phosphatase (ALP) activity, in samples of serum from patients with primary trigeminal neuralgia (TN), and investigate the associations between them. Results from 73

Dalfampridine may activate latent trigeminal neuralgia in patients with multiple sclerosis.

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OBJECTIVE To determine the effect of dalfampridine (4-aminopyridine), a broad-spectrum, voltage-dependent potassium channel blocker, on patients with trigeminal nerve dysfunction due to multiple sclerosis (MS). METHODS We reviewed histories of 71 patients in our clinic with clinically definite MS

The role of large-conductance, calcium-activated potassium channels in a rat model of trigeminal neuropathic pain.

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BACKGROUND Trigeminal neuralgia is a disorder of paroxysmal and severely disabling facial pain and continues to be a real therapeutic challenge. At present there are few effective drugs. Here the aim of this study was to investigate the role of BKCa channels in trigeminal neuropathic

[The effect of gabapentin in bucco-facial allodynia. Experimental correlation of the trigeminal nerve].

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BACKGROUND Trigeminal neuralgia is an unilateral alteration of the trigeminal nerve, characterized by recurrent paroxysms of pain in one or more of the nerve's branches. Trigger areas are described in points of the facial skin (allodynia). OBJECTIVE To evaluate the effects of gabapentin

Positive neurologic phenomena with initiation of dalfampridine for multiple sclerosis.

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OBJECTIVE Review cases of positive neurologic phenomena initiated or worsened with dalfampridine in patients with multiple sclerosis. BACKGROUND Oral, extended release dalfampridine (4-aminopyridine or 4-AP) is a potassium-channel blocker approved for the treatment of gait impairment in multiple

[Pharmacological action of siwei shaoyao decoction].

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The Siwei Shaoyao Decoction possesses a marked effect on the alleviation of trigeminal neuralgia in rats caused by penicillin G potassium injection. As shown from the hot-plate test, it also has an obvious analgesic effect on mice. To some extent, the decoction has a significant anti-inflammatory

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