Effect of Preoperative Diclofenac Potassium on Postoperative Endodontic Pain
Parole chiave
Astratto
Descrizione
Patients with moderate-to-severe preoperative pain are selected. Patients receive either a single-dose of 50 mg diclofenac potassium (group A) or a placebo tablet as a control (group B). All patients receive the assigned premedication one hour before single-visit root canal treatment. Postoperative endodontic pain is measured at the following time points: 6 , 12,24,48 h after treatment. The incidence of analgesic intake is also recorded.
Date
| Ultimo verificato: | 03/31/2018 |
| Primo inviato: | 11/04/2017 |
| Iscrizione stimata inviata: | 11/09/2017 |
| Primo pubblicato: | 11/13/2017 |
| Ultimo aggiornamento inviato: | 04/05/2018 |
| Ultimo aggiornamento pubblicato: | 04/08/2018 |
| Data di inizio effettiva dello studio: | 11/30/2016 |
| Data di completamento primaria stimata: | 01/31/2018 |
| Data stimata di completamento dello studio: | 03/31/2018 |
Condizione o malattia
Intervento / trattamento
Drug: Diclofenac Potassium 50mg tab
Drug: Placebo
Fase
Gruppi di braccia
| Braccio | Intervento / trattamento |
|---|---|
| Experimental: Diclofenac Potassium 50mg tab Diclofenac Potassium 50mg tablet to be administered one hour before treatment. | Drug: Diclofenac Potassium 50mg tab A 50 mg tablet of the medication to be taken one hour before initiation of endodontic treatment. |
| Placebo Comparator: Placebo Placebo to be administered one hour before treatment. | Drug: Placebo A placebo will be taken one hour before initiation of endodontic treatment. |
Criteri di idoneità
| Età idonea per lo studio | 18 Years Per 18 Years |
| Sessi idonei allo studio | All |
| Accetta volontari sani | sì |
| Criteri | Inclusion Criteria: - Patients with active pain (moderate-to-severe) in mandibular molars. - Patients with prolonged response to cold testing and electric pulp tester. - Patient with the ability to understand and use pain scales. - Patient with vital coronal pulp tissue on access. - Patient who accept to enroll to the study. Exclusion Criteria: - Patients' allergies or any other contraindication to diclofenac potassium or articaine. - Pregnant and lactating females. - Patients having pain medication in the last 6 hours. - Patient has more than one symptomatic mandibular tooth in the same quadrant. - Patients with periradicular pathosis and/or radiolucency other than widened periodontal ligaments. - Patients with active peptic ulcer and gastrointestinal disorders. - Patients with history of bleeding problems or anticoagulant use within the last month. |
Risultato
Misure di esito primarie
1. Postoperative endodontic pain [Up to 2 days after endodontic treatment]
Misure di esito secondarie
1. Analgesic intake [Up to 2 days after endodontic treatment]
