Re-craniotomy and Complications After Elective Neurosurgery
Parole chiave
Astratto
Descrizione
Demographic data include age, gender, preoperative neurological assessment, diagnosis, operation, surgical position, ASA physical status, dexamethasone requirement, anticonvulsant therapy, airway assessment, and blood component reservation.
Intraoperative information contain anesthetic technique, total dosage of propofol, fentanyl, and other anesthetic agents, total blood loss, types and amount of fluid replacement, volume of blood transfusion, latest body temperature, and the ability of safe extubation.
Postoperative complications will be categorized in to general conditions, neurological complications, and systemic problems. General conditions such as on endotracheal tube overnight and postoperative blood transfusion. Neurological complications include worsen increased ICP, intracranial hematoma, seizures, newly-developed motor deficit, cranial nerve palsy, CSF rhinorrhea, and emergency re-craniotomy. Systemic problems are hypothermia, electrolyte imbalance, anemia, hypertension, and hyperglycemia. Postoperative nausea and vomiting and the rescued anti-emetic drugs will be recorded. Postoperative anti-epileptic drug (AED) and pain medication will be collected.
Date
| Ultimo verificato: | 03/31/2019 |
| Primo inviato: | 04/05/2019 |
| Iscrizione stimata inviata: | 04/07/2019 |
| Primo pubblicato: | 04/09/2019 |
| Ultimo aggiornamento inviato: | 04/10/2019 |
| Ultimo aggiornamento pubblicato: | 04/11/2019 |
| Data di inizio effettiva dello studio: | 12/31/2016 |
| Data di completamento primaria stimata: | 01/31/2019 |
| Data stimata di completamento dello studio: | 01/31/2019 |
Condizione o malattia
Intervento / trattamento
Drug: Propofol
Fase
Gruppi di braccia
| Braccio | Intervento / trattamento |
|---|---|
| no complication the patients who did not develop any kind of complication and no re-craniotomy | |
| with complication (s) the patients who developed at least one of non-neurological complication or required re-craniotomy |
Criteri di idoneità
| Età idonea per lo studio | 18 Years Per 18 Years |
| Sessi idonei allo studio | All |
| Metodo di campionamento | Non-Probability Sample |
| Accetta volontari sani | sì |
| Criteri | Inclusion Criteria: - Patients who are scheduled for elective craniotomy during 2017-2019 - Patients who are planned for general anesthesia - Patients have read the study information and signed in the consent form Exclusion Criteria: - Patients who are unable to understand and sign in the consent form - Patients who are scheduled for minor surgical procedures such as ventriculostomy and VP-shunt |
Risultato
Misure di esito primarie
1. re-craniotomy [the first 24 hours]
2. predictive factors of re-craniotomy [the first 24 hours]
Misure di esito secondarie
1. incidence of major non-neurological complications [the first 24 hours]
2. predictive factors of major non-neurological complications [the first 24 hours]
