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Asian Pacific Journal of Tropical Medicine 2014-Sep

Bioprospecting medicinal plants for antioxidant components.

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Il collegamento viene salvato negli appunti
Ahmed Yacouba Coulibaly
Rokiah Hashim
Shaida Fariza Sulaiman
Othman Sulaiman
Lily Zuin Ping Ang
Kheng Leong Ooi

Parole chiave

Astratto

OBJECTIVE

To evaluate antioxidant activities of seven medicinal plant species and their fractions, and to identify their phenolic compounds.

METHODS

Two extractions were processed and further fractionated by column chromatography to evaluate the concentration that inhibit 50% of 2,2'-azinobis (3-ethylbenzothiazoline-6-suslfonic acid, 1,1-diphenyl-2-picryl-hydrazyl radicals, and their ferric reducing antioxidant power. The identification of the fractions of phenolic compounds was done by ultra performance liquid chromatography.

RESULTS

The aqueous-acetone extracts of Feretia apodanthera and Ozoroa insignis exhibited the highest antioxidant potentials comparable to those of the standard quercetin. Their subsequently silica gel column fractionation showed three most active fractions from which the major constituents quercetin, myricetin, kampferol, rutin and isoquercetin were identified.

CONCLUSIONS

These plant species have potent antioxidant profiles and polyphenol compounds that may help to manage with radical related disease and aging.

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