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Zhongguo Zhongyao Zazhi 2009-Aug

[Chemical constituents from Corydalis yanhusuo].

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Tiantian Hu
Xue Zhang
Shizhong Ma
Yiyu Cheng
Xinsheng Yao

Parole chiave

Astratto

OBJECTIVE

To study the chemical constituents from the 60% ethanol extract of Corydalis yanhusuo.

METHODS

The chemical constituents were separated and purified by various chromatographic techniques, and their structures were elucidated by chemical evidence and spectroscopic analysis.

RESULTS

Nine alkaloids were obtained and determined as 7-formyldidehydroglaucine (1), nantenine (2), (+)-O-methylbulbocapnine (3), d-corydaline (4), tetrahydrocoptisine (5), 8-oxocoptisine (6), palmatine (7), tetrahydropalmatine (8), and dehydrocorydaline (9), respectively.

CONCLUSIONS

Compound 1 was obtained from natural products for the first time, and its NMR data were firstly reported. Compound 3 was reported from Papaveraceae for the first time, and compound 6 was firstly reported from Corydalis yanhusuo.

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