Yao xue xue bao = Acta pharmaceutica Sinica 2003-May
[Chemical constituents in the roots of Salvia przewalskii Maxim].
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OBJECTIVE
To investigate the chemical composition of the root of Salvia przewalskii Maxim.
METHODS
Compounds were isolated by silica gel column chromatography. Structures of these compounds were elucidated by spectral analysis (EI-MS, FAB-MS, 1HNMR, 13CNMR, 1H-1H COSY, 1H-13C COSY, HMBC, NOESY) and phytochemical properties.
RESULTS
Eight compounds were isolated and identified as: tanshinone II-A (I), crypotanshinone (II), przewaquinone A (III), sugiol (IV), ursolic acid (V), 2 alpha, 3 alpha-dihydroxy urs-12-ene-28-acid (VI), oleanolic acid (VII), and neo-przewaquinone A (VIII).
CONCLUSIONS
Compound VIII is a new compound, and compound II, IV, V, VI and VII are isolated from this plant for the first time.
