Zhongguo Zhongyao Zazhi 2002-Apr
[Triterpenoid saponins from bark Mitragyna inermis].
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OBJECTIVE
To study the constituents of Mitragyna inermis that have an anti-tumor activity on Bel-7402 of hepatic carcinoma.
METHODS
The compounds were isolated by column chromatography on silica gel, ODS, Sephadex LH-20 separately and their structures were elucidated by chemical and spectral technology.
RESULTS
Three quinovic acid glycosides, quinovic acid 3 beta-beta-D-glucopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-28-O-beta- D-glucopyranoside(I), quinovic acid 3 beta-O-beta-D-quinovopyranoside(II), quinovic acid 3 beta-O-beta-D-glucopyranoside(III), were obtained.
CONCLUSIONS
I, II were isolated from Mitragyna for the first time.
