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achyranthes rotundifolia/seizures

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Anticonvulsant activity and acute neurotoxic profile of Achyranthes aspera Linn.

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BACKGROUND Root powder of Achyranthes aspera Linn. (A. aspera) belongs to family Amaranthaceae is used in Indian traditional medicine for the management of epilepsy and its efficacy is widely acclaimed among the different rural communities. OBJECTIVE The present study was aimed to establish the

Achyranthes aspera Attenuates epilepsy in experimental animals: possible involvement of GABAergic mechanism.

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The present study was aimed to examine the possible anticonvulsant property of aerial parts of Achyranthes aspera using various experimental models of epilepsy in mice. Petroleum ether extract of aerial parts of A. aspera (PeAA), methanolic eAA (MeAA) and aqueous eAA (AeAA) was initially evaluated
The alcoholic extract of Achyranthes bidentata (AAB) has been studied for analgesic, anticonvulsant and CNS depressant activities in animal models. Analgesic activity was studied using acetic acid-induced writing test for assessing peripheral analgesic effect and tail immersion test for central

Preliminary Screening of a Classical Ayurvedic Formulation for Anticonvulsant Activity.

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BACKGROUND Epilepsy is a serious and complex central nervous system disorder associated with recurrent episodes of convulsive seizures due to the imbalance between excitatory (glutamatergic) and inhibitory (GABAergic) neurotransmitters level in the brain. The available treatments are neither
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