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antigout/obesità

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Benzbromarone aggravates hepatic steatosis in obese individuals.

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As a widely used anti-gout drug, benzbromarone has been found to induce hepatic toxicity in patients during clinical treatment. Previous studies have reported that benzbromarone is metabolized via cytochrome P450, thus causing mitochondrial toxicity in hepatocytes. In this study, we found that

Bioassay screening of Amazonian plants.

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OBJECTIVE The purpose of this study was to evaluate several biological activities of thirty plant extracts collected in the North West Amazon (Ecuador). Some of these plants are being used for their reputed medicinal properties by the natives of this region. METHODS Five in vitro bioassays were used
BACKGROUND Obese patients with preoperative gout often suffer of gouty attacks after bariatric surgery (BS), probably due to the lack of an adequate postoperative diet. OBJECTIVE The objectives of the study are to assess whether sleeve gastrectomy (SG) is effective in reducing the frequency of gouty

Cherry consumption and decreased risk of recurrent gout attacks.

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OBJECTIVE To study the relationship between cherry intake and the risk of recurrent gout attacks among individuals with gout. METHODS We conducted a case-crossover study to examine the associations of a set of putative risk factors with recurrent gout attacks. Individuals with gout were

Nocturnal risk of gout attacks.

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OBJECTIVE Several plausible mechanisms and anecdotal descriptions suggest that gout attacks often occur at night, although there are no scientific data supporting this. We undertook this study to evaluate the hypothesis that gout attacks occur more frequently at night. METHODS We conducted a
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