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aristolactam/saururus
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6 risultati
Aristolactam BII of Saururus chinensis attenuates glutamate-induced neurotoxicity in rat cortical cultures probably by inhibiting nitric oxide production.
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Saurolactam and aristolactam BII, aristolactam-type alkaloids isolated from the aerial part of Saururus chinensis (Lour.) Ball (Saururaceae), showed significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells. The action mechanism of aristolactam
[Chemical constituents of Saururus chinensis (Lour.) Bail].
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OBJECTIVE
To search for the active chemical constituents of Saururus chinensis.
METHODS
95% ethanol extracts from the aerial part of Saururus chinensis was mixed with silica gel, and then eluted with petroleum ether, ethyl acetate and methanol. On the basis of physicochemical properties and
Chemistry of Saururus cernuus, V. sauristolactam and other nitrogenous constituents.
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Two aristololactam analogues were isolated from the extract of Saururus cernuus. One of these was the known aristololactam BII [1] (cepharanone B) and the other new, named sauristolactam [2], was shown to be the lactam of 10-aminomethyl-3-hydroxy-4-methoxyphenanthrene-1-carboxylic acid. Here we
Anti-proliferative neolignans from Saururus chinensis against human cancer cell lines.
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Activity-guided fractionation of an 80% EtOH extract from the aerial parts of Saururus chinensis led to isolation of three anti-proliferative neolignans (1-3) along with four flavonoids (4-7) and four aristolactams (8-11). Their chemical structures were identified by analysis of spectroscopic data.
Simultaneous determination of eleven bioactive compounds in Saururus chinensis from different harvesting seasons by HPLC-DAD.
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A high performance liquid chromatography method coupled with diode array detection (HPLC-DAD) was developed for simultaneous determination of five major active flavonoids, two aristolactams and four main lignans in Saururus chinensis, namely rutin (1), isoquercitrin (2),
Simultaneous determination of four amides in Saururus chinensis by matrix solid phase dispersion and high-performance liquid chromatography method.
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A rapid and simple analytical method was established for the determination of four amides (N-p-trans-coumaroyltyramine, aristolactam AⅡ, sauristolactam and aristolactam BⅡ) in Saururus chinensis by matrix solid phase dispersion (MSPD) and high-performance liquid chromatography-diode array detector
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