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arteannuin/cancro
Il collegamento viene salvato negli appunti
5 risultati
Progress in research on the anti-tumor effect of artesunate.
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It has been found in recent years that Artesunate (Art), a water soluble derivative of arteannuin, mainly previously used for its anti-malarial activity, has some other effects, e.g. it could act as an anti-tumor agent by way of inducing cell apoptosis, antagonizing angiogenesis, reversing
Dihydroartemisinin is an inhibitor of ovarian cancer cell growth.
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OBJECTIVE
To investigate the anticancer activity of dihydroartemisinin (DHA), a derivative of antimalaria drug artemisinin in a panel of human ovarian cancer cell lines.
METHODS
Cell growth was determined by the MTT viability assay. Apoptosis and cell cycle progression were evaluated by a DNA
Cytotoxic terpenoids and flavonoids from Artemisia annua.
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The cytotoxic activity of nine terpenoids and flavonoids isolated from Artemisia annua was tested in vitro on several human tumor cell lines. These compounds are artemisinin, deoxyartemisinin, artemisinic acid, arteannuin-B, stigmasterol, friedelin, friedelan-3 beta-ol, artemetin, and quercetagetin
Effects of sesquiterpene, flavonoid and coumarin types of compounds from Artemisia annua L. on production of mediators of angiogenesis.
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BACKGROUND
In addition to recognized antimalarial effects, Artemisia annua L. (Qinghao) possesses anticancer properties. The underlying mechanisms of this activity are unknown. The aim of our experiments was to investigate the effects of distinct types of compounds isolated from A. annua on the
Antitumor activity of an Artemisia annua herbal preparation and identification of active ingredients.
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