asthenozoospermia/phosphatase

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Adnexal gland secretion markers in unexplained asthenozoospermia.

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Prostatic acid phosphatase, prostate-specific antigen, and zinc as markers of prostate, and fructose as marker of seminal vesicles were investigated in the seminal plasma of 35 idiopathic asthenozoospermic and 20 normal subjects to evaluate their relationship with sperm motility. Total seminal

[Identification of asthenozoospermia-associated proteins in human seminal plasma by shotgun proteomic strategy].

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OBJECTIVE To identify asthenozoospermia-associated proteins in seminal plasma by the shotgun proteomic strategy. METHODS Six seminal plasma samples were collected by Percoll respectively from healthy fertile and asthenozoospermia volunteers, balanced, mixed, and then the mixture was separated by

Impaired secretory function of the prostate in men with oligo-asthenozoospermia.

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The secretory function of the human prostate and the seminal vesicles is a prerequisite for gel formation and liquefaction of semen, but the relation to poor sperm motility and low sperm count in infertile men remains to be clarifyed. Our aim was to evaluate the secretory function of the prostate

[Azoospermia, asthenozoospermia and seminal biochemistry].

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The biochemical analysis of human semen is based on assays of certain compounds in the ejaculate, which are secreted by the prostate (acid phosphatase, citrate, zinc), the seminal vesicles (fructose), and the epididymis (free carnitine). The information provided by seminal biochemistry is relevant

Biochemical correlates of asthenozoospermia: a lesion at the level of the sperm adenylyl cyclase.

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Studies of the adenylyl cyclase in spermatozoa from 10 asthenozoospermic and 10 normal men revealed major differences with regard to the activation of the enzyme by various drugs and metal ions. While the response to acetate ions was normal, activation of the enzyme by forskolin and the GTP analogue

Influence of low corrected seminal fructose levels on sperm chromatin stability in semen from men attending an infertility service.

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OBJECTIVE To determine any correlation between sperm chromatin stability under sodium dodecyl sulfate (SDS), and SDS-ethylendiamine tetraacetic acid (SDS and EDTA) conditions with levels of corrected seminal fructose, obtained multiplying logarithm of sperm count by seminal fructose concentration,

Biochemical analysis of electroejaculates in spinal cord injured men: comparison to normal ejaculates.

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To address the consistent finding of asthenospermia in spinal cord injured men we compared the biochemical constituents of antegrade fractions of electroejaculates of 6 such patients with the manual ejaculates of 6 volunteers. Semen samples in each group were analyzed for 19 biochemical parameters,

Selective ablation of Ppp1cc gene in testicular germ cells causes oligo-teratozoospermia and infertility in mice.

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The four isoforms of serine/threonine phosphoprotein phosphatase 1 (PP1), derived from three genes, are among the most conserved proteins known. The Ppp1cc gene encodes two alternatively spliced variants, PP1 gamma1 (PPP1CC1) and PP1 gamma2 (PPP1CC2). Global deletion of the Ppp1cc gene, which causes

Human Epididymis Protein 4 Quantification and Interaction Network Analysis in Seminal Plasma.

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A well-known tissue marker of ovarian cancer, Human Epididymis protein 4 (HE4) is the member of whey acidic four-disulfide core proteins family. Purified from human seminal plasma and characterized as a cross-class protease inhibitor, HE4 was proposed to shield spermatozoa against

[Tamoxifen treatment of oligospermia. Mechanism of action and metabolism].

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210 males with idiopathic oligozoospermia or oligo-astheno-teratozoospermia were treated with tamoxifen (2 X 10 resp. 2 X 20 mg daily) over a period of five months. Investigations which were performed concomitantly revealed no significant changes in body weight, blood pressure, blood sedimentation

Phosphatidylinositol 3-kinase inhibition enhances human sperm motility.

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BACKGROUND The number of spermatozoa with forward motility after capacitation procedures represents the limiting factor for application of IVF versus intracytoplasmatic sperm injection (ICSI) procedure in cases of oligoasthenozoospermia. The possibility of increasing this number may thus be of help

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