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conessine/dissenteria
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5 risultati
[Experimental studies on conessine. II. Elimination of conessine in man during treatment of amebic dysentery].
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Liquid chromatography-tandem mass spectrometry method for the quantification of a potent H3 receptor antagonist conessine in serum and its application to pharmacokinetic studies.
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Conessine, a steroidal alkaloid obtained from the bark and seeds of the plant species of Apocynaceae family, elicits a histamine antagonistic action, selectively for the H3 histaminergic receptors. This alkaloid is used mainly for the treatment of dysentery and helminthic disorders. For the
Conessine as a novel inhibitor of multidrug efflux pump systems in Pseudomonas aeruginosa.
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BACKGROUND
Holarrhena antidysenterica has been employed as an ethnobotanical plant for the treatment of dysentery, diarrhoea, fever, and bacterial infections. Biological activities of the principle compound, conessine including anti-diarrhoea and anti-plasmodial effects were documented. Our previous
Alkaloid production by plant cell suspension cultures of Holarrhena antidysenterica: I. Effect of major nutrients.
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The effect of major nutrients on growth and alkaloid production by plant cell culture of Holarrhena antidysenterica was studied with a view to increasing the yield of the alkaloid conessine, a therapeutic drug used for treatment of dysentery and helminthic disorders. The studies resulted in
Chromatographic analysis of Kutajarista--an ayurvedic polyherbal formulation.
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Kutajarista is a well known polyherbal preparation of which the main ingredient is the stem bark of Holarrhena antidysenterica. This Ayurvedic medicine is prescribed to treat amoebic dysentery and other disorders such as fever, indigestion and malabsorption syndrome. Herbal medicines are very
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