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corneal neovascularization/potassio
Il collegamento viene salvato negli appunti
Pagina 1 a partire dal 28 risultati
Subconjunctival injection of low-molecular-weight heparin-taurocholate 7 inhibits corneal neovascularization.
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OBJECTIVE
To evaluate the effects of a subconjunctival injection of low-molecular-weight heparin-taurocholate 7 (LHT7) on corneal neovascularization (CoNV) in rats.
METHODS
Twenty-four Sprague-Dawley rats were divided into 4 groups of 6 animals each. Corneal centers were cauterized by the
Inhibition of corneal angiogenesis by ascorbic acid in the rat model.
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OBJECTIVE
To evaluate the effect of topically administered ascorbic acid on experimentally induced corneal neovascularization in the rat model.
METHODS
Corneal chemical cauterization of 72 eyes in Long-Evans male rats was performed using silver nitrate/potassium nitrate sticks. Nine groups of eight
The inhibitory effects of trastuzumab on corneal neovascularization.
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OBJECTIVE
To investigate the effect of systemic administration of trastuzumab in the prevention of experimentally induced corneal neovascularization in a rat model.
METHODS
An experimental animal study.
METHODS
Sixteen male Wistar-Albino rats weighing 250 g to 300 g were used in the study. Silver
Effect of subconjunctival bevacizumab (Avastin) on experimental corneal neovascularization in guinea pigs.
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OBJECTIVE
To evaluate the effect of subconjunctival bevacizumab (Avastin) on experimental corneal neovascularization in guinea pigs.
METHODS
Forty eyes of 40 guinea pigs were chemically cauterized with 75% silver nitrate and 25% potassium nitrate sticks. Fifteen eyes (group 1) received 2
Prevention and treatment of corneal neovascularization: comparison of different doses of subconjunctival bevacizumab with corticosteroid in experimental rats.
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BACKGROUND
To evaluate and compare the effect of different doses of subconjunctival bevacizumab with betamethasone on the development of corneal major new vessels in a rat model of corneal chemical injury.
METHODS
The right eyes of 100 male Sprague-Dawley rats were randomly divided into 10
In vivo measurement of corneal angiogenesis with video data acquisition and computerized image analysis.
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BACKGROUND
Measurement of corneal angiogenesis is useful for quantitating the effects of angiogenic stimuli and for evaluating the efficacy of potential inhibitors of neovascularization. Because accurate methods to record the entire pattern of corneal neovascularization over time in individual
The effect of combinations of flurbiprofen, low molecular weight heparin, and doxycycline on the inhibition of corneal neovascularization.
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OBJECTIVE
To determine the efficacy of various combinations of flurbiprofen, low molecular weight heparin (LMWH), and doxycycline on the inhibition of corneal neovascularization in rats.
METHODS
Chemical cauterization of the cornea in 32 eyes of 32 rats was performed using silver nitrate/potassium
Attenuation of corneal neovascularization by topical low-molecular-weight heparin-taurocholate 7 without bleeding complication.
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OBJECTIVE
To investigate the antiangiogenic effects and safety of topically administered low-molecular-weight heparin-taurocholate 7 (LHT7) on corneal neovascularization (CoNV).
METHODS
Twenty-four Sprague-Dawley rats were randomly distributed into four groups of six rats each. The central corneas
Effect of Histone Deacetylase Inhibitor, Butyroyloxymethyl-Diethyl Phosphate (AN-7), on Corneal Neovascularization in a Mouse Model.
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To examine whether butyroyloxymethyl-diethyl phosphate (AN-7), a histone deacetylase inhibitor, inhibits chemically induced corneal neovascularization (NV) in mice.
Corneal NV was induced in the right eye of male C57BL mice by application of a mixture of 75% silver nitrate and 25% potassium nitrate
Retrobulbar anesthesia and eyelid closure--effect on corneal angiogenesis.
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We evaluated the effect of corneal anesthesia produced by retrobulbar injections of bupivicaine and epinephrine on corneal neovascularization in the rat. The eyelids were sutured closed to prevent dessication and ulceration of the insensitive corneas. The amount of corneal neovascularization induced
Quantitation of corneal neovascularization using computerized image analysis.
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We have developed a method for quantitating corneal neovascularization, induced in anesthetized rats by silver nitrate/potassium nitrate cauterization, using a LeMont OASYS video input image analyzer. Corneal vessels are visualized by perfusing the upper half of deeply anesthetized animals with a
Effect of inhibitors of arachidonic acid metabolism on corneal neovascularization in the rat.
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We used computerized image analysis to evaluate quantitatively the ability of topically applied corticosteroids (dexamethasone sodium phosphate, prednisolone acetate), cyclooxygenase inhibitors (flurbiprofen, indomethacin, ketorolac), lipoxygenase inhibitors (REV 5901, esculetin, quercetin), and
Corneal angiogenesis based on different protocols of alkaline cauterization in murine models.
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UNASSIGNED
To establish and compare protocols of alkaline cauterization for inducing corneal angiogenesis in murine models.
UNASSIGNED
Twenty-four adult Wistar rats were distributed into four groups (G1, G2, G3, and G4). The right eye cornea from each rat was cauterized using filter paper (3 mm),
Prevention of corneal neovascularization: evaluation of various commercially available compounds in an experimental rat model.
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OBJECTIVE
To evaluate the effect of topically administered agents doxycycline, triamcinolone, low molecular weight heparin (LMWH), and flurbiprofen on experimental corneal neovascularization in rats.
METHODS
Chemical cauterization of cornea was performed in 36 eyes of 36 rats by using silver
Effect of subconjunctival and intraocular bevacizumab injections on corneal neovascularization in a mouse model.
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OBJECTIVE
This study sought to evaluate the efficacy of bevacizumab (Avastin), an anti-VEGF agent, in the reduction of corneal neovascularization in a rodent model, and compare between the effect of intraocular and subconjunctival injection.
METHODS
Corneal neovascularization was induced by
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