daphnoretin/daphne

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ArticoliTest cliniciBrevetti

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7 risultati

[Simultaneous determination of daphnetin, daphnoretin, daphneticin in rat plasma by LC-MS/MS and its application in pharmacokinetic study].

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To establish HPLC-MS/MS method for simultaneous determination of daphnetin, daphnoretin, and daphneticin in rat plasma after oral and intravenous administration of Daphne giraldii extract, and then use them in the calculation of pharmacokinetic parameters. Six sprague-dawley rats received

[Chemical constituents of Daphne odora var. margirmta].

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OBJECTIVE To study the chemical constituents of Daphne odora var. margirmta. METHODS The compounds were isolated and purified by column chromatography of silica gel, ODS, Sephadex LH-20, and their structures were identified by UV, 1H-NMR, 13C-NMR, MS and CD spectroscopic methods. RESULTS Ten

[Studies on the chemical constituents in roots of Daphne odora var. atrocaulis].

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OBJECTIVE To study the chemical constituents from Daphne odora var. atrocaulis. METHODS The chemical constituents were isolated and repeatedly purified by silica gel column chromatography and the structures were elucidated by the NMR spectra and physicochemical properties. RESULTS Sixteen compounds

[Studies on chemical constituents of Daphne genkwa].

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OBJECTIVE To study the chemical constituents of the flower buds of Daphne genkwa. METHODS The constituents of petroleum ether and ethyl acetate-soluble portions were isolated and purified by means of chromatography, then they were identified by their physico-chemical characteristics and spectral

[Chemical constituents from rhizome of Daphne papyracea var. crassiuscula].

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OBJECTIVE To study chemical constituents from rhizome of Daphne papyracea var. crassiuscula. METHODS Ethyl acetate fraction of 75% ethanol extracts from rhizome of D. papyracea var. crassiuscula, and its strucutre was identified by spectral method. RESULTS Nine compounds were separated and

Isolation of flavonoids, a biscoumarin and an amide from the flower buds of Daphne genkwa and the evaluation of their anti-complement activity.

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As part of an ongoing study aimed at identifying the anti-complement active compound from the flower buds of Daphne genkwa, ten flavonoids, one biscoumarin and one amide were isolated. Their structures were identified from spectroscopic and physicochemical data as genkwanin 5-O-beta-d-primveroside

Antimicrobial evaluation of coumarins and flavonoids from the stems of Daphne gnidium L.

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The antimicrobial activity of stems methanol extract from Daphne gnidium L. collected from Sardinia (Italy) was evaluated against 6 strains of standard and clinical isolated gram (+/-) bacteria. The antimicrobial effect on two strains of fungi was also tested. The extract in toto exhibited

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