epispadias/testosterone

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Low-dose Human Chorionic Gonadotropin Stimulation Test as a Prognostic Incontinent Indicator in Boys With Bladder Exstrophy-epispadias Complex.

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OBJECTIVE To investigate the effect of low-dose human chorionic gonadotropin (HCG) administration on structural changes in the lower urinary tract in boys with urinary incontinence in the setting of bladder exstrophy-epispadias complex (BEEC). METHODS We prospectively evaluated 30 patients (median

The Tunica Vaginalis Flap as an Adjunct to Epispadias Repair: A Preliminary Report.

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OBJECTIVE To report our preliminary institutional experience of incorporating a tunica vaginalis flap (TVF) as an adjunct into primary or secondary epispadias repair. METHODS A prospectively maintained institutionally approved database of exstrophy-epispadias complex patients was used to identify

The use of parenteral testosterone therapy in genital reconstructive surgery.

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Previously, testosterone cream has been used for penile enlargement before genital surgery. The results not only were inconsistent but the absorption was variable. Therefore, we elected to study the use of parenteral testosterone as an adjunct before reconstructive surgery. In 44 patients with

The use of human chorionic gonadotropin (HCG) for penile reconstruction in bladder exstrophy and total epispadias patients.

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OBJECTIVE The effect of intramuscular human chorionic gonadotropin (HCG) administration on penile enlargement before genital surgery, its influence on penile skin histology and testicular descent were investigated. METHODS We examined 45 male patients (median age, 8 months; range 3-28) with total

Plasma testosterone values in hypopspadiacs.

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The plasma testosterone values were determined by radioimmunoassay in a group of 42 patients with a severe form of hypospaida, in one case of epispadia, in a control group of 69 boys with an adequate development of sex organs, and in 48 well fertile men. It was found that the beginning of pubescence

[Plasma testosterone values in patients with somatosexual development disturbances from 11 years old to adulthood].

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The testosterone plasma level was determined in 5 groups: 1. in 69 normal juveniles and 85 fertile males at the age of 11 to 45 years, 2. in 42 patients with hypospadia or epispadia aged 11 to 25 years, 3. in 72 males with unilateral cryptorchidism at the age of 11 to 45 years, 4. in 83 males with

Y chromosome aberration in a patient with cloacal-bladder exstrophy-epispadias complex: an unusual finding.

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Chromosome aberrations or genetic syndromes associated with cloacal-bladder exstrophy complex have rarely been reported. The aim of this report is to describe a 14 year-old female Brazilian patient with a complex urogenital malformation, short stature, lack of secondary se-xual characteristics and Y

Complete repair of bladder exstrophy in the newborn: complications and management.

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OBJECTIVE Complete repair of bladder exstrophy in the newborn includes bladder, and posterior and penile urethral closure, along with epispadias repair and abdominal wall closure without bladder neck reconstruction. While reports have shown the need for early reimplantation of the ureters in 50% of

The newborn exstrophy bladder inadequate for primary closure: evaluation, management and outcome.

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OBJECTIVE The surgical approach to the small newborn exstrophy bladder inadequate for primary closure remains undetermined. Various methods for long-term management have been implemented. We evaluated our experience with late primary closure of the small exstrophied bladder template. METHODS Our

The failed complete repair of bladder exstrophy: insights and outcomes.

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OBJECTIVE We describe the complications of complete repair and their management. METHODS A total of 19 patients were referred after failed complete repair. Total dehiscence occurred in 6 males, major bladder prolapse in 3, minor prolapse in 3, pubic separation in 1, impassable stricture in 1, and

Etiology, clinical profile, gender identity and long-term follow up of patients with ambiguous genitalia in India.

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There is little information on the profile of children with ambiguous genitalia in India. Presented here is an analysis of patients with ambiguous genitalia registered in a general endocrine clinic during the last 2 decades. Seventy-four patients (age 4 months to 36 years) were registered during

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