Patients receive the stereotactic infarct tissue aspiration 24-48 hours after cerebral infarction beside medical therapy.

osmotic therapy with mannitol and glycerol fructose，anti-platelet treatment, statins, and other symptomatic treatments such as controlling blood pressure, blood sugar, and infection, and tracheal intubation or incision, etc;

Middle Cerebral Artery Infarction

The patient posed supine position to expose local skin and puncture point was located at 6.5 cm behind the hairline of the lesion side, and 5.0 cm lateral of midline. After routine skin preparation and disinfection, 5% lidocaine 2-5 ml was injected for local anesthesia. The skin was cut to expose periosteum by a scalpel. After skull was vertically drilled through with a 6mm diameter hole, a sterile tube with a needle in tube was put about 8 cm into centrum semiovale. The needle was put out and about 50ml necrosis brain tissue was aspirated by a 20 ml syringe. The tube was fixed into the skin about 2 cm after subcutaneous tunnel, and connected to the drainage bag. Surgical area was sterilized and wrapped by sterile gauze bandage.

Stereotactic infarct tissue aspiration

osmotic therapy with mannitol and glycerol fructose，anti-platelet treatment, statins, and other symptomatic treatments such as controlling blood pressure, blood sugar, and infection, and tracheal intubation or incision, etc

Medical therapy

General hospital of shenyang military region

Stereotactic Infarct Tissue Aspiration for Malignant Infarction of Middle Cerebral Artery

Stereotactic Infarct Tissue Aspiration (SITA) for Malignant Infarction of Middle Cerebral Artery

Hui-Sheng Chen

Director of Neurology Dept.

General Hospital of Shenyang Military Region

AFTER COMPLETING THE INITIAL EVALUATION (ANTHROPOMETRY, SERUM BIOCHEMISTRY AND CML LEVELS, FUNDUS, MUTIFOCAL ELECTRORETINOGRAM AND OPTIC NERVE CONDUCTION VELOCITY) PATIENTS WILL RECEIVE ORAL PLACEBO CAPSULES 4 PER EACH MEAL/DAY DURING 12 WEEKS

AFTER COMPLETING THE CONTROL PERIOD (PLACEBO CAPSULES) PATIENTS WILL BE REASSESSED, AND THEN TREATED WITH ORAL CHOLESTYRAMINE 6 G/DAY (500 MG CAPSULES -> 4 CAPSULES PER EACH MEAL/DAY) DURING 12 WEEKS AND E SAME INITIAL EVALUATION WILL BE REPEATED

DIABETES

DIABETIC RETINOPATHY

DIABETIC NEUROPATHY

CHOLESTYRAMINE CAPSULES, 6 G/DAY P.O. DURING 12 WEEKS

CHOLESTYRAMINE

Institute of Nutrition & Food Technology (INTA)

Clinica Alemana de Santiago

PRELIMINARY EVALUATION OF PHARMACOLOGICAL LOWERING OF AGEs

PRELIMINARY EVALUATION OF RETINAL EFFECTS OF PHARMACOLOLOGICAL LOWERING OF SERUM LEVES OF ADVANCED GLYCATION END-PRODUCTS (AGEs) IN TYPE 2 DIABETIC PATIENTS

REDUCTION OF CARBOXYMETHYL (CML) SERUM LEVELS

CHANGE IN OPTICAL NERVE CONDUCTION AFTER VISUAL STIMULUS RESPECT PLACEBO

MARIA PIA DE LA MAZA

Professor

University of Chile

Prescription of 6 g oral cholestiramine in 7 patients with type 2 DM, to study changes in neuroophtalmologic variables (electroretinogram and optic nerve conduction)

fructose/edema

Stereotactic Infarct Tissue Aspiration for Malignant Infarction of Middle Cerebral Artery

PRELIMINARY EVALUATION OF PHARMACOLOGICAL LOWERING OF AGEs

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