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geographic atrophy/nicotina

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Nicotine reduces VEGF-secretion and phagocytotic activity in porcine RPE.

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OBJECTIVE Smoking is a strong environmental factor for the development of age-related macula degeneration. In this study, we investigated the effects of nicotine on RPE cell function in porcine in vitro models, focussing on cell death, VEGF secretion and phagocytotic ability. METHODS For these

Environmental tobacco smoke exposure and eye disease.

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OBJECTIVE To undertake a systematic review of the literature on the effect of environmental tobacco smoke (ETS) and eye disease. METHODS Medline (1950-January Week 2 2007), EMBASE (1980 to 2007 Week 07), SCOPUS and Science Direct were searched on ETS exposure and eye disease using various

Age-related macular degeneration and mortality: the Melbourne Collaborative Cohort Study.

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AimsTo assess associations between features of age-related macular degeneration (AMD) and mortality.MethodsA total of 21 129 participants from the Melbourne Collaborative Cohort Study aged 47-85 years (60% female) were assessed for AMD (2003-2007). Mortality data to December 31, 2012 were obtained

Smoking and age-related maculopathy. The Blue Mountains Eye Study.

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OBJECTIVE To assess the associations between stage of age-related maculopathy (ARM) and current, past, and passive smoking. METHODS A cross-sectional study of 3654 subjects from a defined geographic area west of Sydney, Australia, identified subjects with late age-related macular degeneration (AMD)

Risk factors for age-related macular degeneration: Pooled findings from three continents.

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OBJECTIVE To assess the prevalence and potential risk factors for late age-related macular degeneration (AMD) in three racially similar populations from North America, Europe, and AUSTRALIA: METHODS Combined analysis of population-based eye disease prevalence data. METHODS There were 14,752
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