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hydroxyacetophenone/edema
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5 risultati
p-Hydroxyacetophenone suppresses nuclear factor-κB-related inflammation in nociceptive and inflammatory animal models.
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p-Hydroxyacetophenone (HAP) is a crucial chemical compound present in plants of the genus Artemisia, which are used in traditional therapies for treating jaundice, hepatitis, and inflammatory diseases. Nevertheless, the bioactivity of HAP remains to be identified in order to prove its importance in
Phytochemical study and anti-inflammatory properties of Lampaya hieronymi Schum. ex Moldenke.
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The chemical study of aerial parts of Lampaya hieronymi Schum. ex Moldenke yielded oleanolic acid, epi-oleanolic acid, epi-maslinic acid, 4'7-dimethoxyapigenin, p-hydroxyacetophenone, and p-hydroxyacetophenone-beta-glucoside. In searching for natural products as potential anti-inflammatory agents,
[Synthesis and anti-inflammatory activity of ursolic acid derivative-chalcone conjugates].
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A series of novel conjugates with ursolic acid core and different chalcone ligands were synthesized via ursolic acid, 4-hydroxyacetophenone and aromatic aldehydes. All of the conjugates were confirmed by the application of IR, (1)H NMR, (13C) NMR and HR-MS. The anti-inflammatory effect was observed
Pharmacological profile of a novel, orally active leukotriene B4 antagonist, SM-15178.
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SM-15178, a new hydroxyacetophenone derivative, was evaluated to determine its antiinflammatory activity and antagonistic activity against leukotriene B4 (LTB4). SM-15178 inhibited [3H]LTB4 binding to its receptors on human neutrophils (IC50 = 0.30 microM). It inhibited LTB4-induced chemotaxis of
Analgesic and Anti-Inflammatory Activities of the Ethanolic Extract of Artemisia morrisonensis Hayata in Mice.
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The aim of this study was to investigate the possible analgesic and anti-inflammatory mechanisms of the ethanolic extract of A. morrisonensis Hayata (AM(EtOH)). Two models were employed for evaluation of the analgesic effects: acetic acid-induced writhing response and formalin-induced paw licking.
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