isopropyl alcohol/epatite

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Disinfection of Goldmann tonometers after contamination with hepatitis C virus.

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OBJECTIVE To compare methods of disinfecting Goldmann tonometer tips inoculated with hepatitis C virus. METHODS Hepatitis C virus was placed on Goldmann tonometer tips, air dried, and then disinfected by dry gauze wipes, isopropyl alcohol wipes, cold water washes, povidone iodine 10% wipes, and

Hepatitis C Contamination of Medication Vials Accessed with Sterile Needles and Syringes.

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Health care-associated hepatitis C virus outbreaks from contaminated medication vials continue to be reported even though most practitioners deny reusing needles or syringes. The hypothesis was that when caring for hepatitis C virus-infected patients, healthcare providers may

Inactivation of hepatitis B virus by intermediate-to-high-level disinfectant chemicals.

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In five separate tests, hepatitis B virus in dried human plasma was exposed for 10 min at 20 degrees C to disinfectant chemicals having activity levels ranging from intermediate (e.g., 70% isopropyl alcohol) to high (e.g., 2% aqueous glutaraldehyde at pH 8.6). Five chimpanzees (one animal per

Carbon tetrachloride toxicity potentiated by isopropyl alcohol. Investigation of an industrial outbreak.

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Fourteen workers in an isopropyl alcohol packaging plant became ill after accidental exposure to carbon tetrachloride. In four, renal failure or hepatitis developed. Isopropyl alcohol potentiation of carbon tetrachloride toxicity has been shown previously only in rats. Acetone, a product of

Outbreak of carbon tetrachloride poisoning in a color printing factory related to the use of isopropyl alcohol and an air conditioning system in Taiwan.

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Three workers from a color printing factory were admitted to community hospitals in 1985 with manifestations of acute hepatitis. One of the three had superimposed acute renal failure and pulmonary edema. An investigation was subsequently conducted at the plant to determine the etiology of the

Ethanol enhances hepatitis C virus replication through lipid metabolism and elevated NADH/NAD+.

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Ethanol has been suggested to elevate HCV titer in patients and to increase HCV RNA in replicon cells, suggesting that HCV replication is increased in the presence and absence of the complete viral replication cycle, but the mechanisms remain unclear. In this study, we use Huh7 human hepatoma cells

Stereoselective synthesis of PSI-352938: a β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyl-3',5'-cyclic phosphate nucleotide prodrug for the treatment of HCV.

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PSI-352938 is a novel 2'-deoxy-2'-α-fluoro-2'-β-C-methyl 3',5'-cyclic phosphate nucleotide prodrug currently under investigation for the treatment of hepatitis C virus (HCV) infection. PSI-352938 demonstrated superior characteristics in vitro that include broad genotype coverage, superior resistance

Disinfection of Tonometers: A Report by the American Academy of Ophthalmology.

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To examine the efficacy of various disinfection methods for reusable tonometer prisms in eye care and to highlight how disinfectants can damage tonometer tips and cause subsequent patient harm. Literature searches were conducted last in October 2016 in the PubMed and the Cochrane Library databases

Antimicrobial activity of a new intact skin antisepsis formulation.

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Different antiseptic formulations have shown limitations when applied to disinfecting intact skin, notably short-term tolerability and/or efficacy. The purpose of this study was optimizing a new antiseptic formulation specifically targeted at intact skin disinfection and evaluating its in vitro

Virucidal activity of 2 alcohol-based formulations proposed as hand rubs by the World Health Organization.

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The virucidal activity of 2 hand rubs proposed by the World Health Organization was studied in a quantitative suspension test for chemical disinfectants and antiseptics in human medicine (EN 14476). These formulations are recommended if no hand rubs with declared microbiological activity are

Survey of infection control procedures at manicure and pedicure establishments in North York.

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OBJECTIVE To describe infection control practices used by technicians doing manicures and pedicures in an urban setting in Ontario. METHODS A random sample of 120 establishments was selected from a sampling frame. A survey was designed and administered to technicians through face-to-face

Disinfection of tonometers and contact lenses in the office setting: are current techniques adequate?

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OBJECTIVE To determine whether routine office techniques used to disinfect tonometer prisms and trial contact lenses are sufficient to prevent transmission of ocular infections. METHODS We reviewed the current literature on the efficacy of certain disinfection protocols against commonly encountered

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