7 risultati
Study Description: Soluble epoxide hydrolase (sEH) is the metabolizing enzyme of epoxyeicosatrienoic acids (EETs), which may play a role in reducing neuroinflammation and regulating cerebral blood flow after subarachnoid hemorrhage (SAH).
Hypothesis: Pharmacologic inhibition of the sEH enzyme is
Inclusion Criteria:
- Over the age of 59
- Gender and Age-Matched (within 3 years) of main protocol participants
Exclusion Criteria:
- Parkinson's disease diagnosis
- Significant cognitive deficits.
- Another neurological or orthopedic deficit that in the investigator's opinion would have a
Subjects are recruited as patients in one of the neurology, neurosurgery or neuro-oncology clinics at OHSU. There are four groups of the study:
- Subjects receive the combidex infusion only.
- Subjects receive Combidex and undergo a previously schedule neurosurgery.
- Subjects undergo surgery only
Background: The diagnosis of GH deficiency in adults is established by provocative testing of GH secretion. The insulin tolerance test (ITT) is widely regarded as the gold standard test for diagnosing adult GH deficiency despite concerns about its practicality, safety, reproducibility, and its
Research Objectives:
The primary objective is to apply an effective medical weight loss treatment to post bariatric surgery patients to enhance their weight loss through stimulation of thermogenesis and lipolysis and retention of lean body mass. This treatment using ephedrine with phosphodiesterase
Individuals with Parkinson's disease (PD) have a higher risk of death from coronary artery disease and stroke (Gorell, Johnson, & Rybicki, 1994; Postuma & Lang, 2004). Seventy percent of people with PD suffer from dementia or cognitive impairment. Decreased levels of B vitamins are linked to