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osteopetrosis/carbohydrate
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3 risultati
Osteopetrosis in obese female rats is site-specifically inhibited by physical training.
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What is the central question of this study? Clinical studies suggest that obesity 'protects' against osteoporosis. However, these studies used only bone densitometry and assessed only one bone site, which is insufficient to enable conclusions to be drawn about the response of the whole
Lectin histochemistry of infantile lysosomal storage disease associated with osteopetrosis.
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In infantile lysosomal storage disease associated with osteopetrosis the nature of the enzyme deficiency as well as the type of material accumulated are both unknown. We used lectin histochemistry to characterize the storage material of previously reported cases. Using paraffin sections neurons
Severe neurodegeneration with impaired autophagy mechanism triggered by ostm1 deficiency.
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Loss of Ostm1 leads to the most severe form of osteopetrosis in mice and humans. Because functional rescue of the osteopetrotic defect in these mice extended their lifespan from ∼3 weeks to 6 weeks, this unraveled a second essential role of Ostm1. We discovered that Ostm1 is highly expressed in the
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