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oxyacanthine/berberis aquifolium
Il collegamento viene salvato negli appunti
5 risultati
Lipoxygenase inhibition and antioxidant properties of bisbenzylisoqunoline alkaloids isolated from Mahonia aquifolium.
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Products of lipoxygenase metabolism are known to play a role in the pathogenesis of psoriasis. Six bisbenzylisoquinoline (BBIQ) alkaloids, oxyacanthine, armoline, baluchistine, berbamine, obamegine, aquifoline, isolated from Mahonia aquifolium, were tested for lipoxygenase inhibition. Berbamine and
Effect of bisbenzylisoquinoline alkaloids from Mahonia aquifolium on the isolated rat aorta.
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1. The extract from roots of Mahonia aquifolium as well as berbamine and oxyacanthine relaxed K(+)-precontracted rat aortal rings with IC50 values of about 20 mumol/l. 2. Relaxation was not inhibited by denudation of the endothelium or by premedication of the aortas with indomethacin, methylene blue
The antipsoriatic Mahonia aquifolium and its active constituents; I. Pro- and antioxidant properties and inhibition of 5-lipoxygenase.
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The effects of the extract of the bark of Mahonia aquifolium and its main constituents (berberine, berbamine, oxyacanthine) on 5-lipoxygenase, lipid peroxidation in phospholipid liposomes induced by 2,2'-azo-(bis-2-amidinopropane), deoxyribose degradation, and their reactivities against the free
Antimicrobial activity of Mahonia aquifolium and two of its alkaloids against oral bacteria.
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Extracts or alkaloids isolated from Mahonia aquifolium exhibit antimicrobial activity against Gram-positive and Gram-negative bacteria, fungi, and protozoa. In this study the bacteriostatic and bacteriocidal activities of a M. aquifolium extract and two of its major alkaloids, berberine chloride and
The antipsoriatic Mahonia aquifolium and its active constituents; II. Antiproliferative activity against cell growth of human keratinocytes.
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The extract of the bark of Mahonia aquifolium is an inhibitor of keratinocyte growth with an IC50 of 35 microM. Of its main alkaloids tested, berberine inhibited cell growth to the same extent as did the Mahonia extract, while the benzylisoquinoline alkaloids berbamine and oxyacanthine were more
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