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4 risultati
2-Methyl 2-butanol suppresses human retinoblastoma cells through cell cycle arrest and autophagy.
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2-Methyl-2-butanol (MBT) is a chemical compound from the group of alcohols more specifically pentanols, which has shown an excellent anti-cancer activity in our previous study. However, its mechanism of action remains unclear. The present study was designed to investigate the anti-cancer effect of
ELISA assays and alcohol: increasing carbon chain length can interfere with detection of cytokines.
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Enzyme-linked immunosorbent assays (ELISAs) are frequently used in studies on cytokine production in response to treatment of cell cultures or laboratory animals. When an ELISA assay is performed on cell culture supernatants, samples often contain the treatment agents. The purpose of the present
Exhaled Volatile Organic Compounds during Inflammation Induced by TNF-α in Ventilated Rats
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Systemic inflammation alters the composition of exhaled breath, possibly helping clinicians diagnose conditions such as sepsis. We therefore evaluated changes in exhaled breath of rats given tumor necrosis factor-alpha (TNF-α). Thirty male Sprague-Dawley rats were randomly assigned to three groups
Short chain aliphatic beta-nitro alcohols for corneoscleral cross-linking: corneal endothelial toxicity studies.
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OBJECTIVE
Recent studies suggest that short chain aliphatic beta-nitro alcohols can cross-link corneoscleral tissue under physiologic conditions. The present study was conducted to determine the cytotoxic threshold for these agents in vitro and to draw comparisons to commonly used topical ophthalmic
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