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piperolactam a/piper
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5 risultati
Pharmacoinformatics study of Piperolactam A from Piper betle root as new lead for non steroidal anti fertility drug development.
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Fertility control is a burning problem all over the world to regulate population overflow and maintain ecological balance. This study is an in-silico approach to explore a non-steroidal lead as contraceptive agent in order to avoid several contraindications generated by steroidal analogues.
In Vitro susceptibilities of wild and drug resistant Leishmania donovani amastigotes to piperolactam A loaded hydroxypropyl-β-cyclodextrin nanoparticles.
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Leishmaniasis is an epidemic in various countries, and the parasite Leishmania donovani is developing resistance against available drugs. In the present study the antileishmanial action of piperolactam A (PL), isolated after bioactivity guided fractionation from root extracts of Piper betle was
[Chemical constituents from Piper longum].
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OBJECTIVE
To study the chemical constituents of Piper longum.
METHODS
The whole plant of air-dried P. longum was extracted with 95% EtOH. The EtOH extract was suspended in H2O and extracted with petroleum ether, CHCl3 and n-BuOH, successively. The compounds were isolated and purified by column
A new hydroxychavicol dimer from the roots of Piper betle.
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A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these
[Chemical constituents from twigs of Piper hancei].
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OBJECTIVE
To investigate the chemical constituents from the twigs of Piper hancei.
METHODS
The chemical constituents were isolated and purified by means of chromatographic techniques including silica gel,Sephadex LH-20 and preparative RP-HPLC. Their structures were elucidated on the basis of
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