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Pagina 1 a partire dal 18 risultati
Nerve stimulation methods for averting imminent onset or episode of a disease
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BACKGROUND OF THE INVENTION
The field of the present invention relates to the delivery of energy impulses (and/or fields) to bodily tissues for prophylactic purposes. It relates more specifically to the use of non-invasive devices and methods for transcutaneous electrical nerve stimulation and
Substituted quinoxaline-2-ones as glutamate receptor antagonists
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BACKGROUND OF THE INVENTION
This invention is for novel glutamate receptor antagonists which are new compounds of the substituted quinoxaline 2-ones type. The compounds are active as excitatory amino acid receptor antagonists acting at glutamate receptors, including either or both
Sulfonamide derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists
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BACKGROUND OF THE INVENTION
The present invention concerns novel sulfonamide derivatives of substituted quinoxaline 2,3-diones having utility as glutamate receptor antagonists. The fused ring quinoxaline 2,3-dione system is substituted at the a- or b-position by sulfonamide derivatives. The
Cyclic amine derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists
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BACKGROUND OF THE INVENTION
This invention is for novel glutamate receptor antagonists which are new compounds of the 5,6,7,8-substituted quinoxaline 2,3-diones type. The fused ring system is substituted at the a or b position by amino acid derivatives. The compounds are active as excitatory amino
Substituted [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a national phase of International Application No. PCT/US2014/027450 filed on Mar. 14, 2014, which claims the benefit of U.S. Provisional Application No. 61/785,478 filed on Mar. 14, 2013, each of which are incorporated herein by reference
Pyridone derivatives
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This application is a U.S. national stage of International Application No. PCT/JP03/03115 filed Mar. 14, 2003.
TECHNICAL FIELD
The present invention is useful in medical fields. In more detail, novel pyridone derivatives of the present invention have an effect as neuropeptide Y receptor antagonists
Diaryl-substituted five-membered heterocycle derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a U.S. National Phase application under 35 U.S.C. .sctn.371 of PCT Application No. PCT/JP2005/004379, filed Mar. 7, 2005, which claims priority under 35 U.S.C. .sctn.119 from JP Application No. JP2004-062343, filed Mar. 5, 2004.
TECHNICAL
Cranial nerve stimulation treatments using neurocybernetic prosthesis
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FIELD OF THE INVENTION
The present invention generally relates to methods for treating, controlling or preventing medical, psychiatric or neurological disorders by application of modulating electrical signals to a selected nerve or nerve bundle of a patient, and more particularly to techniques for
Therapeutic uses of polymers and oligomers comprising gamma-hydroxybutyrate
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BACKGROUND TO THE INVENTION
The present invention is generally in the field of therapeutic formulations for delivering gamma-hydroxybutyrate.
Gamma-hydroxybutyrate ("GHB") is a naturally occurring substance that is widely distributed in the mammalian body, being present, for example, in the brain,
Biaryl derivatives
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a U.S. National Phase application under 35 U.S.C. .sctn.371 of PCT Application No. PCT/JP2005/012442, filed Jun. 29, 2005, which claims priority under 35 U.S.C. .sctn.119 from JP Application No. JP2004-194410, filed Jun. 30, 2004.
TECHNICAL
Nerve stimulation methods for averting imminent onset or episode of a disease
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Entra registrati
BACKGROUND OF THE INVENTION
The field of the present invention relates to the delivery of energy impulses (and/or fields) to bodily tissues for prophylactic purposes. It relates more specifically to the use of non-invasive devices and methods for transcutaneous electrical nerve stimulation and
7-piperidinoalkyl-3, 4-Dihydroquinolone derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This is a National Stage of International Application No. PCT/JP2009/067441 filed Sep. 30, 2009, claiming priority based on Japanese Patent Application No. 2008-257072 filed Oct. 2, 2008, the contents of all of which are incorporated herein by reference in
Urea and thiourea derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists
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FIELD OF THE INVENTION
The present invention concerns novel urea and thiourea derivatives of substituted quinoxaline 2,3-diones having utility as glutamate receptor antagonists. The fused ring quinoxaline 2,3-dione system is substituted at the a- or b-position by urea or thiourea derivatives. The
Isoquinoline derivatives or salts thereof
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TECHNICAL FIELD
The present invention relates to drugs, particularly to novel isoquinoline derivatives or salts having a I.sub.f current inhibitory effect without serious side effects such as convulsion and also to drugs, particularly cardiac rate lowering agents containing these compounds as the
Amide derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists
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BACKGROUND OF THE INVENTION
The present invention concerns novel amide derivatives of substituted quinoxaline 2,3-diones having utility as glutamate receptor antagonists. The fused ring quinoxaline 2,3-dione system is substituted at the a- or b-position by amide derivatives. The compounds are active
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