7 risultati
New inhibitors of ethanol absorption, E-senegasaponins a and b, Z-senegasaponins a and b, Z-senegins II and III, were isolated from Senegae Radix, the roots of Polygala senega L. var latifolia Torrey et Gray, together with senegins II and III. Their chemical structures have been elucidated on the
The hypoglycemic effect of the rhizomes of Polygala senega L. var. latifolia Torrey et Gray (Polygalaceae) was investigated in normal and KK-Ay mice, one of the model animals of non-insulin dependent diabetes mellitus (NIDDM). The n-butanol extract of senega rhizomes (SN) (5 mg/kg) reduced the blood
The hypoglycemic effect of senegin-II, the main component of Polygala senega (Polygalaceae), was examined in normal and KK-Ay mice, one of the model animals of non-insulin-dependent diabetes mellitus (NIDDM). Senegin-II (2.5 mg/kg) reduced the level of blood glucose in normal mice from 220 +/- 8 to
Following the characterization of E-senegasaponins a and b and Z-senegasaponins a and b, new bioactive saponins named E-senegasaponin c and Z-senegasaponin c were isolated from Senegae Radix, the root of Polygala senega L. var. latifolia TORREY et GRAY., together with Z-senegins II, III, and IV. The
OBJECTIVE
The chemical differences of Polygala tenuifolia varieties-JinYuan 1 (JY1), FenYuan 2 (FY2) and traditional FenYang (FY) were studied, in order to provide reference for the breeding of Polygala tenuifolia.
METHODS
The samples of JY1, FY2 and FY were subjected to ultra-high performance
Senegasaponins [senegin II (1), senegin III (2), senegin IV (3), senegasaponin a (4), and senegasaponin b (5)] from Polygala senega were re-discovered as selective anti-proliferative substances against human umbilical vein endothelial cells (HUVECs). Senegasaponins (1-5) showed anti-proliferative
Four triterpenoid glycosides isolated from the rhizomes of Polygala senega var. latifolia, senegins II-IV (1-3) and desmethoxysenegin II (4), were tested for hypoglycemic activity in normal and KK-Ay mice. Compounds 1 and 2 reduced the blood glucose of normal mice 4 h after intraperitoneal