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Pagina 1 a partire dal 131 risultati
Evaluation of hemostatic behavior of micro and nano gelatin/silica hybrid in severe bleeding.
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The pH variation of the injury site is an important factor in the failure of styptic and its structural damage. In this study, the behaviour of a gelatin-silica hybrid in severe bleeding was evaluated under different pH values. On the other hand, the effect of the hybrid particle size, which is one
Intracranial biodegradable silica-based nimodipine drug release implant for treating vasospasm in subarachnoid hemorrhage in an experimental healthy pig and dog model.
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Nimodipine is a widely used medication for treating delayed cerebral ischemia (DCI) after subarachnoid hemorrhage. When administrated orally or intravenously, systemic hypotension is an undesirable side effect. Intracranial subarachnoid delivery of nimodipine during aneurysm clipping may be more
A Novel Droplet-Fabricated Mesoporous Silica-Based Nanohybrid Granules for Hemorrhage Control.
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Uncontrolled hemorrhage is one of the leading cause for death in both civilian and military trauma. The zeolite-based hemostatic agent currently available in clinic exhibits great exothermic reaction and poor biodegradability. To overcome these limitations, in this study, we developed a novel
Mesoporous silica nanoparticles carried on chitosan microspheres for traumatic bleeding control.
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Chitosan has been made into various hemostats, but their hemostatic efficiency for controlling severe traumatic bleeding is still inadequate. The aim of this work is to make quick hemostats by incorporating mesoporous silica nanoparticles into chitosan. Porous chitosan-silica composite microspheres
Molecular imprinted macroporous chitosan coated mesoporous silica xerogels for hemorrhage control.
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Efficacious hemostatic agents have significant potential for use in rapid exsanguinating hemorrhage control by emergency medical technician or military medic nowadays. Unfortunately, the topical hemostats currently available in market still have various disadvantages. In this study, a series of
Chitosan-Coated Diatom Silica as Hemostatic Agent for Hemorrhage Control.
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Uncontrolled hemorrhage leads to high death risk both in military and civilian trauma. Current hemostatic agents still have various limitations and side effects. In this study, natural diatom silica obtained from diatomite and diatom culture was purified and developed for hemorrhage control. To
Silver-decorated mesostructured cellular silica foams as excellent antibacterial hemostatic agents for rapid and effective treatment of hemorrhage
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Uncontrolled bleeding, such as deep, narrow or irregular wound hemorrhage, has been a major cause of death in peacetime and wartime. Besides, traditional hemostatic agents are lack of antibacterial properties, which could not provide effective protection on open wound. In this paper, a novel
Degradable, antibacterial silver exchanged mesoporous silica spheres for hemorrhage control.
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Effective hemorrhage control becomes increasingly significant in today's military and civilian trauma, and current available local hemostatic agents have been reported to have various drawbacks and side effects. Herein in this study, a silver exchanged calcium doped ordered mesoporous silica sphere
A highly porous silica and chitosan-based hemostatic dressing is superior in controlling hemorrhage in a severe groin injury model in swine.
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BACKGROUND
This study compared the efficacy of 3 hemostatic dressings in a severe groin injury model in swine.
METHODS
Twenty-three swine received TraumaStat (OreMedix, Lebanon, OR), Chitoflex (HemCon, Inc., Portland, OR), or standard gauze for hemostasis. Complete femoral vessel transections were
[Effect of silica shield intrauterine devices on menstrual blood loss and iron balance].
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Low-Bleed Silica-Based Stationary Phase for Hydrophilic Interaction Liquid Chromatography.
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Bleeding of hydrophilic interaction liquid chromatographic (HILIC) phases is a major problem. A hydrophobic silica surface exhibits low bleeding but does not behave as a HILIC phase. A hydrophilic coating, such as that of poly(vinyl alcohol) (PVA) on a hydrophobic particle should result in a
Smaller silica nanorattles reabsorbed by intestinal aggravate multiple organs damage.
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Recent advances in design and controllable synthesis of rattle-type silica nanoparticles have led to a dramatic expansion of their potential drug delivery application. However, the relationship between physico-chemical parameters and bio-effects of silica nanoparticles is still unclear. In the
High efficiency and simple preparation of polyacrylamide coated silica stationary phase for hydrophilic interaction liquid chromatography.
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A polyacrylamide (PAM)-coated silica packing as a novel stationary phase for hydrophilic interaction liquid chromatography (HILIC) was produced firstly by thermal immobilization. The coated layer was formed by a simple and facile physical method that dipping silica spheres into a PAM solution and
Microscopic polyangiitis associated with pleuropericarditis, pulmonary embolism and pulmonary hemorrhage as a complication of silicosis.
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Silica (silicon dioxide) occupational exposure has been linked to both pulmonary and extra-pulmonary toxicity. Silicosis is the major pulmonary toxicity, which has also been associated with the development of collagen-vascular disease and with anti-neutrophil cytoplasmic antibody (ANCA)-positive
[Cerebral vasospasm and lipid peroxidation--lipid peroxides in the cerebrospinal fluid after subarachnoid hemorrhage].
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The relationship between lipid peroxides in cerebrospinal fluid (CSF) and the occurrence of cerebral vasospasm following subarachnoid hemorrhage (SAH) was evaluated by analyzing CSF with high-performance liquid chromatography (HPLC) and gas chromatography mass spectrometry (GC-MS). Hydroperoxy
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