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sorbic acid/eritema
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8 risultati
Sorbic acid-induced erythema and edema.
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Sorbic acid concentrations as low as 0.1% produced transient erythema with edema and flare after open or closed application to human skin. Multiple areas of the body were tested. Reactions were most intense on the face but also could be produced on the back, forearm, and deltoid areas. Sorbic
Sorbic acid: a cause of immediate nonallergic facial erythema. An update.
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Release of markedly increased quantities of prostaglandin D2 from the skin in vivo in humans following the application of sorbic acid.
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METHODS
Sorbic acid is a preservative that can induce cutaneous vasodilation characterized by erythema, urticaria, and stinging when applied topically to humans. Previous studies have suggested that prostaglandins may mediate the vasodilation, but the prostaglandin responsible has not been
An animal model for nonimmunologic contact urticaria.
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The suitability of the guinea pig for studies on nonimmunologic contact urticaria (NICU) was investigated. Groups of five, female Hartley guinea pigs were challenged by applying 50 microliters of various concentrations of human NICU agents, benzoic acid (BA), sorbic acid (SA), cinnamic acid (CA),
Skin irritation by dithranol cream. A blind study to assess the role of the cream formulation.
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In connection with a national cost-effective evaluation study of short contact dithranol therapy for psoriasis, the question arose whether dithranol cream irritation is influenced by constituents of the vehicle. To establish the role of the different components of the vehicle in the mechanism of
Release of markedly increased quantities of prostaglandin D2 from the skin in vivo in humans after the application of cinnamic aldehyde.
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BACKGROUND
Cinnamic aldehyde is a common fragrance additive in foods and various health and beauty products. Application of cinnamic aldehyde to the skin of humans can induce cutaneous vasodilatation characterized by erythema, urticaria, and stinging. Previous studies have suggested that
Topical benzoic acid induces the increased biosynthesis of prostaglandin D2 in human skin in vivo.
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BACKGROUND
Benzoic acid is one of the most commonly used preservatives in cosmetics, foodstuffs, and drug preparations. Nonetheless, products containing this compound frequently induce cutaneous erythema. Previous studies have suggested that prostaglandins may mediate the cutaneous vasodilation
Mechanisms of subjective (sensory) irritation. Propensity to non-immunologic contact urticaria and objective irritation in stingers.
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Subjective (sensory) irritation was studied with lactic acid test on 74 females; 8 reacted positively with "stinging" and/or itching or burning and another 5 had mild subjective sensations. History of previous corresponding sensations from contact with cosmetic products was significantly more common
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